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LEBRUN Laura

Main Referenced Co-authors
WILMES, Paul  (35)
MAY, Patrick  (22)
LACZNY, Cedric Christian  (20)
MULLER, Emilie  (18)
BUSCHART, Anna  (15)
Main Referenced Keywords
metatranscriptomics (3); activated sludge (2); Biomolecular isolation (2); Integrated omics (2); metagenomics (2);
Main Referenced Unit & Research Centers
Luxembourg Centre for Systems Biomedicine (LCSB): Eco-Systems Biology (Wilmes Group) (16)
Luxembourg Centre for Systems Biomedicine (LCSB): Bioinformatics Core (R. Schneider Group) (10)
Luxembourg Centre for Systems Biomedicine (LCSB): Medical Translational Research (J. Schneider Group) (5)
ULHPC - University of Luxembourg: High Performance Computing (5)
IBBL - Integrated BioBank of Luxembourg (1)
Main Referenced Disciplines
Microbiology (29)
Environmental sciences & ecology (18)
Genetics & genetic processes (9)
Biochemistry, biophysics & molecular biology (3)
Biotechnology (2)

Publications (total 36)

The most downloaded
1175 downloads
Heintz, A., May, P., Laczny, C. C., Lebrun, L., Bellora, C., Krishna, A., Wampach, L., Schneider, J., Hogan, A., de Beaufort, C., & Wilmes, P. (2016). Integrated multi-omics of the human gut microbiome in a case study of familial type 1 diabetes. Nature Microbiology, 2, 16180. doi:10.1038/NMICROBIOL.2016.180 https://hdl.handle.net/10993/28958

The most cited

198 citations (Scopus®)

Heintz, A., May, P., Laczny, C. C., Lebrun, L., Bellora, C., Krishna, A., Wampach, L., Schneider, J., Hogan, A., de Beaufort, C., & Wilmes, P. (2016). Integrated multi-omics of the human gut microbiome in a case study of familial type 1 diabetes. Nature Microbiology, 2, 16180. doi:10.1038/NMICROBIOL.2016.180 https://hdl.handle.net/10993/28958

DELOGU, F., Kunath, B. J., Queirós, P. M., HALDER, R., LEBRUN, L., Pope, P. B., MAY, P., Widder, S., MULLER, E., & WILMES, P. (2023). Forecasting the dynamics of a complex microbial community using integrated meta-omics. Nature Ecology and Evolution. doi:10.1038/s41559-023-02241-3
Peer Reviewed verified by ORBi

Kunath, B., Hickl, O., Teixeira Queiros, P., Martin-Gallausiaux, C., Lebrun, L., Halder, R., Laczny, C. C., Schmidt, T. S., Hayward, M., Becher, D., Heintz-Buschart, A., de Beaufort, C., Bork, P., May, P., & Wilmes, P. (2022). Alterations of oral microbiota and impact on the gut microbiome in type 1 diabetes mellitus revealed by integrated multi-omic analyses. Microbiome. doi:10.1186/s40168-022-01435-4
Peer Reviewed verified by ORBi

Delogu, F., Kunath, B., Queirós, P. M., Halder, R., Lebrun, L., Pope, P. B., May, P., Widder, S., Muller, E. E. L., & Wilmes, P. (2022). Forecasting of a complex microbial community using meta-omics. ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/52862. doi:10.1101/2022.10.19.512887

Brunhoferova, H., Venditti, S., Laczny, C. C., Lebrun, L., & Hansen, J. (26 March 2022). Bioremediation of 27 Micropollutants by Symbiotic Microorganisms of Wetland Macrophytes. Sustainability, 14 (7), 3944. doi:10.3390/su14073944
Peer Reviewed verified by ORBi

Trezzi, J.-P., Aho, V., Jäger, C., Schade, S., Janzen, A., Hickl, O., Kunath, B., Thomas, M., Schmit, K., Garcia, P., Sciortino, A., Martin-Gallausiaux, C., Halder, R., Huarte, O. U., Heurtaux, T., Heins-Marroquin, U., Gomez-Giro, G., Weidenbach, K., Delacour, L., ... Wilmes, P. (2022). An archaeal compound as a driver of Parkinson’s disease pathogenesis. (1). ORBilu-University of Luxembourg. https://orbilu.uni.lu/handle/10993/51987. doi:10.21203/rs.3.rs-1827631/v1

Martinez Arbas, S., Narayanasamy, S., Herold, M., Lebrun, L., Hoopmann, M. R., Li, S., Lam, T. J., Kunath, B. J., Hicks, N. D., Liu, C. M., Price, L. B., Laczny, C. C., Gillece, J. D., Schupp, J. M., Keim, P. S., Moritz, R. L., Faust, K., Tang, H., Ye, Y., ... Wilmes, P. (2021). Roles of bacteriophages, plasmids and CRISPR immunity in microbial community dynamics revealed using time-series integrated meta-omics. Nature Microbiology, 6 (1), 123--135. doi:10.1038/s41564-020-00794-8
Peer Reviewed verified by ORBi

Martinez Arbas, S.* , Narayanasamy, S.* , Herold, M., Lebrun, L., Hoopmann, M. R., Li, S., Lam, T. J., Kunath, B., Hicks, N. D., Liu, C. M., Price, L. B., Laczny, C. C., Gillece, J. D., Schupp, J. M., Keim, P. S., Moritz, R. L., Faust, K., Tang, H., Ye, Y., ... Wilmes, P. (2020). Roles of bacteriophages, plasmids and CRISPR immunity in microbial community dynamics revealed using time-series integrated meta-omics. Nature Microbiology.
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Herold, M., Martinez Arbas, S., Narayanasamy, S., Sheik, A. R., Kleine-Borgmann, L. A. K., Lebrun, L., Kunath, B., Roume, H., Bessarab, I., Williams, R. B. H., Gillece, J. D., Schupp, J. M., Keim, P. S., Jäger, C., Hoopman, M. R., Moritz, R. L., Ye, Y., Li, S., Tang, H., ... Wilmes, P. (2020). Integration of time-series meta-omics data reveals how microbial ecosystems respond to disturbance. Nature Communications. doi:10.1038/s41467-020-19006-2
Peer Reviewed verified by ORBi

Martinez Arbas, S., Narayanasamy, S., Herold, M., Lebrun, L., Hicks, N. D., Price, L. B., Gillece, J. D., Schupp, J. M., Lam, T., Laczny, C. C., Ye, Y., Keim, P. S., Muller, E. E. L., May, P., & Wilmes, P. (19 October 2018). Critical transitions in microbial communities: mobile genetic elements as drivers of the microbial community dynamics within activated sludge of wastewater treatment [Poster presentation]. PhD days 2018, Belval, Luxembourg.

Trezzi, J.-P., Ramiro Garcia, J., Laczny, C. C., Daujeumont, A., Halder, R., Lebrun, L., Heintz, A., Oertel, W., Mollenhauer, B., & Wilmes, P. (October 2018). Microbiome-derived Multi-omicBiomarkers for Early-stage Detection and Stratification of Parkinson's Disease [Poster presentation]. 4th International Parkinson's Disease Symposium.

Martinez Arbas, S., Narayanasamy, S., Herold, M., Lebrun, L., Hicks, N. D., Price, L. B., Gillece, J. D., Schupp, J. M., Laczny, C. C., Keim, P. S., Muller, E. E. L., May, P., & Wilmes, P. (11 September 2018). A multi-omic view of invasive genetic elements and their linked prokaryotic population dynamics within a mixed microbial community [Poster presentation]. ECCB Athens, Athens, Greece.

Herold, M., Narayanasamy, S., Martinez Arbas, S., Muller, E., Kleine-Borgmann, A. L., Lebrun, L., Roume, H., Sheik, A., Bessarab, I., Williams, R., Gillece, J., Schupp, J., Keim, P., Jäger, C., Hoopmann, M., Li, S., Tang, H., Heintz, A., May, P., ... Wilmes, P. (August 2018). Integrated time-resolved multi-omics for understanding microbial niche ecology [Poster presentation]. 17th International Symposium on Microbial Ecology, Leipzig, Germany.

Chaib De Mares, M., Jimenez, D. J., Palladino, G., Gutleben, J., Lebrun, L., Muller, E., Wilmes, P., Sipkema, D., & van Elsas, J. D. (2018). Expressed protein profile of a Tectomicrobium and other microbial symbionts in the marine sponge Aplysina aerophoba as evidenced by metaproteomics. Scientific Reports, 8 (1), 11795. doi:10.1038/s41598-018-30134-0
Peer Reviewed verified by ORBi

Shah, P., Muller, E., Lebrun, L., Wampach, L., & Wilmes, P. (2018). Sequential Isolation of DNA, RNA, Protein, and Metabolite Fractions from Murine Organs and Intestinal Contents for Integrated Omics of Host-Microbiota Interactions. In Microbial Proteomics. United States: Springer. doi:10.1007/978-1-4939-8695-8_19

Muller, E.* , Narayanasamy, S.* , Zeimes, M., Laczny, C. C., Lebrun, L., Herold, M., Hicks, N. D., Gillice, J. D., Schupp, J. M., Keim, P., & Wilmes, P. (18 October 2017). First draft genome sequence of a strain belonging to the Zoogloea genus and its gene expression in situ. Standards in Genomic Sciences, 12 (64). doi:10.1186/s40793-017-0274-y
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Laczny, C. C., Muller, E., Heintz, A., Herold, M., Lebrun, L., Hogan, A., May, P., de Beaufort, C., & Wilmes, P. (2016). Identification, recovery, and refinement of hitherto undescribed population-level genomes from the human gastrointestinal tract. Frontiers in Microbiology, 7 (884). doi:10.3389/fmicb.2016.00884
Peer Reviewed verified by ORBi

Heintz, A., May, P., Laczny, C. C., Lebrun, L., Bellora, C., Krishna, A., Wampach, L., Schneider, J., Hogan, A., de Beaufort, C., & Wilmes, P. (2016). Integrated multi-omics of the human gut microbiome in a case study of familial type 1 diabetes. Nature Microbiology, 2, 16180. doi:10.1038/NMICROBIOL.2016.180
Peer Reviewed verified by ORBi

Heintz, A., May, P., Laczny, C. C., Lebrun, L., Bellora, C., Krishna, A., Wampach, L., Schneider, J., Hogan, A., Beaufort, C. D., & Wilmes, P. (2016). Erratum: Integrated multi-omics of the human gut microbiome in a case study of familial type 1 diabetes. Nature Microbiology, 2, 16227. doi:10.1038/nmicrobiol.2016.227
Peer Reviewed verified by ORBi

Buschart, A., May, P., Laczny, C. C., Lebrun, L., Wampach, L., Hogan, A., Schneider, J., de Beaufort, C., & Wilmes, P. (March 2015). Integrated omics analyses of the human gut microbiome in a multiplex family study of type 1 diabetes mellitus [Poster presentation]. 5th International Human Microbiome Congress, Luxembourg-City, Luxembourg.

Kaysen, A., Heintz, A., Lebrun, L., Graf, N., Simon, A., Bittenbring, J., Kreis, S., Schneider, J., & Wilmes, P. (March 2015). Changes in the human gastrointestinal microbiome during cancer treatments [Poster presentation]. 5th International Human Microbiome Congress, Luxembourg-City, Luxembourg.

Mathay, C., Hamot, G., Henry, E., Georges, L., Bellora, C., Lebrun, L., de Witt, B., Ammerlaan, W., Buschart, A., Wilmes, P., & Betsou, F. (2015). Method optimization for fecal sample collection and fecal DNA extraction. Biopreservation and Biobanking, 13 (2), 79-93. doi:10.1089/bio.2014.0031
Peer Reviewed verified by ORBi

Roume, H., Buschart, A., Muller, E., May, P., Satagopam, V., Laczny, C. C., Narayanasamy, S., Lebrun, L., Hoopmann, M., Schupp, J., Gillece, J., Hicks, N., Engelthaler, D., Sauter, T., Keim, P., Moritz, R., & Wilmes, P. (2015). Comparative integrated omics: identification of key functionalities in microbial community-wide metabolic networks. Biofilms and Microbiomes, 1 (15007). doi:10.1038/npjbiofilms.2015.7
Peer Reviewed verified by ORBi

Sheik, A., Muller, E., Audinot, J.-N., Lebrun, L., Grysan, P., Guignard, C., & Wilmes, P. (2015). In situ phenotypic heterogeneity among single cells of the filamentous bacterium Candidatus Microthrix parvicella. ISME Journal. doi:10.1038/ismej.2015.181
Peer Reviewed verified by ORBi

Muller, E., Pinel, N., Laczny, C. C., Hoopmann, M., Narayanasamy, S., Lebrun, L., Roume, H., Lin, J., May, P., Hicks, N., Buschart, A., Wampach, L., Liu, C., Price, L., Gillece, J., Guignard, C., Schupp, J., Vlassis, N., Baliga, ... Wilmes, P. (2014). Community-integrated omics links dominance of a microbial generalist to fine-tuned resource usage. Nature Communications. doi:10.1038/ncomms6603
Peer Reviewed verified by ORBi

Sheik, A., Muller, E., Audinot, J.-N., Lebrun, L., Grysan, P., & Wilmes, P. (16 October 2014). In situ single-cell investigations of substrate utilisation by Candidatus Microthrix parvicella [Poster presentation]. Phenotypic heterogeneity and sociobiology of bacterial populations, Irsee, Germany.

Sheik, A., Muller, E., Audinot, J.-N., Lebrun, L., Grysan, P., & Wilmes, P. (29 September 2014). Bet-hedging strategy for substrate usage among single cells of Candidatus Microthrix parvicella? [Paper presentation]. International Society for Microbial Ecology (ISME15), Seoul, South Korea.

Heintz, A., May, P., Laczny, C. C., Lebrun, L., Wampach, L., Hogan, A., Schneider, J., Wilmes, P., & De Beaufort, C. (30 April 2014). Integrated Omic Analyses of the Human Gut Microbiome in a Multiplex Family Study of Type 1 Diabetes Mellitus [Poster presentation]. EMBO|EMBL Symposium: Translating Diabetes.

Kaysen, A., Heintz, A., Lebrun, L., Graf, N., Simon, A., Bittenbring, J., Kreis, S., Schneider, J., & Wilmes, P. (April 2014). Dynamic change of host gastrointestinal microbiome and immune status in relation to mucosal barrier effects during chemotherapy and immune ablative intervention in humans [Poster presentation]. Exploring Human Host-Microbiome Interactions in Health and Disease.

Hugerth, L., Muller, E., Hu, Y., Lebrun, L., Roume, H., Lundin, D., Wilmes, P., & Andersson, A. (2014). Systematic Design of 18S rRNA Gene Primers for Determining Eukaryotic Diversity in Microbial Consortia. PLoS ONE. doi:10.1371/journal.pone.0095567
Peer Reviewed verified by ORBi

Muller, E., Pinel, N., Laczny, C. C., Hoopmann, M., Lebrun, L., Roume, H., May, P., Hicks, N., Liu, C., Price, L., Gillece, J., Guignard, C., Schupp, J., Vlassis, N., Moritz, R., Baliga, N., Keim, P., & Wilmes, P. (2014). Community integrated omics links the dominance of a microbial generalist to fine-tuned resource usage [Paper presentation]. 15th International Symposium on Microbial Ecology.

Muller, E., Pinel, N., Laczny, C. C., Hoopmann, M., Lebrun, L., Roume, H., May, P., Hicks, N., Liu, C., Price, L., Gillece, J., Guignard, C., Schupp, J., Vlassis, N., Moritz, R., Baliga, N., Keim, P., & Wilmes, P. (2014). Community integrated omics links the dominance of a microbial generalist to fine-tuned resource usage [Poster presentation]. Phenotypic heterogeneity and sociobiology of bacterial populations.

Muller, E., Buschart, A., Roume, H., Lebrun, L., & Wilmes, P. (2014). The sequential isolation of metabolites, RNA, DNA, and proteins from a single, undivided mixed microbial community sample. Methods in Enzymology.

Heintz, A., May, P., Lebrun, L., Ferrand, J., Trezzi, J.-P., Collignon, S., Wampach, L., Glaab, E., Laczny, C. C., Martins Conde, P., Kaysen, A., Schneider, J., Hiller, K., Hogan, A., Wilmes, P., & de Beaufort, C. (October 2013). Meta-omic Analyses of the Microbiome in a Family Study of Diabetes Mellitus [Poster presentation]. 2nd International Systems Biomedicine Symposium, Belval, Luxembourg.

Muller, E., Pinel, N., May, P., Hussong, R., Roume, H., Lebrun, L., liu, C., Aziz, M., Price, L., Moritz, R., Schupp, J., Keim, P., & Wilmes, P. (2013). Systematic molecular measurements reveal key microbial populations driving community-wide phenotype [Poster presentation]. 12th Symposium on Bacterial Genetics and Ecology (BAGECO).

Muller, E., Roume, H., Buschart, A., Pinel, N., Laczny, C. C., Satagopam, V., May, P., Lebrun, L., & Wilmes, P. (2013). A model microbial community for Eco-Systems Biology [Poster presentation]. 2nd International Systems Biomedicine Symposium.

Muller, E., Roume, H., Lebrun, L., & Wilmes, P. (27 September 2011). Eco-Systems Biology of Natural Lipid-Accumulating Microbial Communities [Poster presentation]. 1st International Systems Biomedicine Symposium.

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