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Complement C1q is hydroxylated by collagen prolyl 4 hydroxylase and is sensitive to off-target inhibition by prolyl hydroxylase domain inhibitors that stabilize hypoxia-inducible factor.

Kiriakidis, Serafim; Hoer, Simon S.; Burrows, Natalie et al.

2017 • In Kidney International, 92 (4), p. 900-908

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