Reference : Cambridge hybrid closed-loop system in very young children with type 1 diabetes reduc... |
Scientific journals : Article | |||
Human health sciences : Endocrinology, metabolism & nutrition | |||
http://hdl.handle.net/10993/52982 | |||
Cambridge hybrid closed-loop system in very young children with type 1 diabetes reduces caregivers’ fear of hypoglycemia and improves their well-being | |
English | |
de Beaufort, Carine [University of Luxembourg > > >] | |
Schierloh, Ulrike [] | |
Thankamony, A. [] | |
Ware, J. [] | |
Wilinska, M.E. [] | |
Fröhlich-Reiterer, E. [] | |
Kapellen, T.M. [] | |
Rami-Merhar [] | |
Hofer, S.E. [] | |
Campbell, F.M. [] | |
Bocchino, L.E. [] | |
Lawton, J. [] | |
Rioze, S. [] | |
Hood, K. [] | |
Frisch, M. [] | |
Thiele, A. [] | |
Allen, J. [] | |
Boughton, C. [] | |
Hovorka, R. [] | |
Pit-Ten Cate, Ineke ![]() | |
4-Oct-2022 | |
Diabetes Care | |
American Diabetes Association | |
45 | |
3050-3053 | |
Yes | |
International | |
0149-5992 | |
1935-5548 | |
Alexandria | |
VA | |
[en] Type 1 Diabetes ; closed loop insulin delivery ; Very young children | |
[en] Objective To evaluate the impact of CamAPS FX hybrid closed-loop automated insulin delivery (HCL) in very young children with type 1 diabetes (T1D) on caregivers’ well-being, fear of hypoglycemia and sleepiness.
Research Design Multinational, open label, randomized crossover study. Children (1-7years) with T1D received treatment for two 4-month periods in random order, comparing HCL with sensor augmented pump (SAP) (control). At baseline and after each treatment period, caregivers were invited to complete WHO-5, Hypoglycemia Fear Survey (HFS) and Epworth Sleepiness Scale (ESS). Results Caregivers of 74 children (mean±SD: age 5±2 years; 42% female, baseline HbA1c 7.3±0.7%) participated. Results revealed significantly lower scores for hypoglycemia fear (p<.001) and higher for well-being (p<.001) after HCL treatment. A trend towards a reduction in sleepiness score was observed (p=0.09). Conclusion Our results suggest a better well-being and less hypoglycemia fear in caregivers of very young children with T1D on CamAPS FX HCL. | |
Researchers ; Professionals | |
http://hdl.handle.net/10993/52982 | |
10.2337/dc22-0693 |
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