| Reference : Cambridge hybrid closed-loop system in very young children with type 1 diabetes reduc... |
| Scientific journals : Article | |||
| Human health sciences : Endocrinology, metabolism & nutrition | |||
| http://hdl.handle.net/10993/52982 | |||
| Cambridge hybrid closed-loop system in very young children with type 1 diabetes reduces caregivers’ fear of hypoglycemia and improves their well-being | |
| English | |
| de Beaufort, Carine [University of Luxembourg > > >] | |
| Schierloh, Ulrike [] | |
| Thankamony, A. [] | |
| Ware, J. [] | |
| Wilinska, M.E. [] | |
| Fröhlich-Reiterer, E. [] | |
| Kapellen, T.M. [] | |
| Rami-Merhar [] | |
| Hofer, S.E. [] | |
| Campbell, F.M. [] | |
| Bocchino, L.E. [] | |
| Lawton, J. [] | |
| Rioze, S. [] | |
| Hood, K. [] | |
| Frisch, M. [] | |
| Thiele, A. [] | |
| Allen, J. [] | |
| Boughton, C. [] | |
| Hovorka, R. [] | |
Pit-Ten Cate, Ineke [University of Luxembourg > Faculty of Humanities, Education and Social Sciences (FHSE) > LUCET >] | |
| 4-Oct-2022 | |
| Diabetes Care | |
| American Diabetes Association | |
| 45 | |
| 3050-3053 | |
| Yes | |
| International | |
| 0149-5992 | |
| 1935-5548 | |
| Alexandria | |
| VA | |
| [en] Type 1 Diabetes ; closed loop insulin delivery ; Very young children | |
| [en] Objective To evaluate the impact of CamAPS FX hybrid closed-loop automated insulin delivery (HCL) in very young children with type 1 diabetes (T1D) on caregivers’ well-being, fear of hypoglycemia and sleepiness.
Research Design Multinational, open label, randomized crossover study. Children (1-7years) with T1D received treatment for two 4-month periods in random order, comparing HCL with sensor augmented pump (SAP) (control). At baseline and after each treatment period, caregivers were invited to complete WHO-5, Hypoglycemia Fear Survey (HFS) and Epworth Sleepiness Scale (ESS). Results Caregivers of 74 children (mean±SD: age 5±2 years; 42% female, baseline HbA1c 7.3±0.7%) participated. Results revealed significantly lower scores for hypoglycemia fear (p<.001) and higher for well-being (p<.001) after HCL treatment. A trend towards a reduction in sleepiness score was observed (p=0.09). Conclusion Our results suggest a better well-being and less hypoglycemia fear in caregivers of very young children with T1D on CamAPS FX HCL. | |
| Researchers ; Professionals | |
| http://hdl.handle.net/10993/52982 | |
| 10.2337/dc22-0693 |
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