Reference : Public Covid-19 X-ray datasets and their impact on model bias - a systematic review o...

	Document type :	Scientific journals : Article
	Discipline(s) :	Engineering, computing & technology : Computer science Engineering, computing & technology : Computer science Engineering, computing & technology : Multidisciplinary, general & others Engineering, computing & technology : Multidisciplinary, general & others Human health sciences : Radiology, nuclear medicine & imaging Human health sciences : Radiology, nuclear medicine & imaging
	Focus Areas :	Systems Biomedicine
	To cite this reference:	http://hdl.handle.net/10993/46439

Title :	Public Covid-19 X-ray datasets and their impact on model bias - a systematic review of a significant problem
Language :	English
Author, co-author :	Garcia Santa Cruz, Beatriz [University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) > >]
	Bossa, Matias Nicolas [University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) > >]
	Sölter, Jan [University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) > Interventional Neuroscience >]
	Husch, Andreas [University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) > Interventional Neuroscience >]
Publication date :	Dec-2021
Journal title :	Medical Image Analysis
Publisher :	Elsevier
Volume :	74
Peer reviewed :	Yes
Audience :	International
ISSN :	1361-8415
e-ISSN :	1361-8423
City :	Amsterdam
Country :	Netherlands
Keywords :	[en] COVID-19 ; machine learning ; datasets ; X-Ray ; imaging ; review ; bias ; confounding ; confounding
Abstract :	[en] Computer-aided diagnosis and stratification of COVID-19 based on chest X-ray suffers from weak bias assessment and limited quality-control. Undetected bias induced by inappropriate use of datasets, and improper consideration of confounders prevents the translation of prediction models into clinical practice. By adopting established tools for model evaluation to the task of evaluating datasets, this study provides a systematic appraisal of publicly available COVID-19 chest X-ray datasets, determining their potential use and evaluating potential sources of bias. Only 9 out of more than a hundred identified datasets met at least the criteria for proper assessment of the risk of bias and could be analysed in detail. Remarkably most of the datasets utilised in 201 papers published in peer-reviewed journals, are not among these 9 datasets, thus leading to models with a high risk of bias. This raises concerns about the suitability of such models for clinical use. This systematic review highlights the limited description of datasets employed for modelling and aids researchers to select the most suitable datasets for their task.
Research centres :	Luxembourg Centre for Systems Biomedicine (LCSB): Systems Control (Goncalves Group) ; Luxembourg Centre for Systems Biomedicine (LCSB): Interventional Neuroscience (Hertel Group)
Funders :	Fonds National de la Recherche - FnR
Name of the research project :	AICovIX
Target :	Researchers ; Professionals
Permalink :	http://hdl.handle.net/10993/46439
	also: http://hdl.handle.net/10993/48108
DOI :	10.1016/j.media.2021.102225
Other URL :	https://www.sciencedirect.com/science/article/pii/S136184152100270X
FnR project :	FnR ; FNR14702831 > Andreas Husch > AICovIX > Ai Based Diagnosis Of Covid-19 From Ct/X-ray Imaging > 01/06/2020 > 30/11/2020 > 2020

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