Modeling metabolism of the human gut microbiome

Reference : Modeling metabolism of the human gut microbiome


	Document type :	Scientific journals : Article
	Discipline(s) :	Life sciences : Multidisciplinary, general & others
	To cite this reference:	http://hdl.handle.net/10993/35685

Title :	Modeling metabolism of the human gut microbiome
Language :	English
Author, co-author :	Magnusdottir, Stefania [University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) > >]
	Thiele, Ines [University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) > >]
Publication date :	2018
Journal title :	Current Opinion in Biotechnology
Publisher :	Elsevier Science
Peer reviewed :	Yes (verified by ORBi^lu)
Audience :	International
ISSN :	0958-1669
Abstract :	[en] The human gut microbiome plays an important part in human health. The complexity of the microbiome makes it difficult to determine the detailed metabolic functions and cross-talk occurs between the individual species. In silico systems biology studies of the microbiome can help to identify metabolite exchanges among gut microbes. Constraint-based reconstruction and analysis methods use biochemically accurate genome-scale metabolic networks of microorganisms to simulate metabolism between species in a given microbiome and help generate novel hypotheses on microbial interactions. Here, we review metabolic modeling studies that have investigated metabolic functions of the gut microbiome.
Permalink :	http://hdl.handle.net/10993/35685
Other URL :	https://www.sciencedirect.com/science/article/pii/S095816691730201X

File(s) associated to this reference

Fulltext file(s):

	File	Commentary	Version	Size	Access
Limited access	1-s2.0-S095816691730201X-main.pdf		Publisher postprint	696.55 kB	Request a copy

All documents in ORBi^lu are protected by a user license.