Reference : Controlling complexity: the clinical relevance of mouse complex genetics.

	Document type :	Scientific journals : Article
	Discipline(s) :	Life sciences : Genetics & genetic processes
	To cite this reference:	http://hdl.handle.net/10993/26639

Title :	Controlling complexity: the clinical relevance of mouse complex genetics.
Language :	English
Author, co-author :	Schughart, Klaus [> >]
	Libert, Claude [> >]
	Kas, Martien J. [> >]
	Andreux, Penelope [> >]
	Aransay, Ana Maria [> >]
	Auwerx, Johan [> >]
	Balling, Rudi [University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) >]
	Banerjee, Sreeparna [> >]
	Bezerianos, Anastasios [> >]
	Bragonzi, Alessandra Desj [> >]
	Brockmann, Gudrun A. [> >]
	Brown, Steve [> >]
	Campbell-Tofte, Joan [> >]
	Cendelin, Jan [> >]
	Chatziioannou, Aristotelis [> >]
	Chen, Duan [> >]
	Crusio, Wim [> >]
	Dimitrakopoulou, Konstantina [> >]
	Falcon, Juan M. [> >]
	Forejt, Jiri [> >]
	Franken, Paul [> >]
	Frohlich, Leopold F. [> >]
	Herault, Yann [> >]
	Hovatta, Iiris [> >]
	Iraqi, Fuad A. [> >]
	Jansen, Ritsert C. [> >]
	Kaczmarek, Leszek [> >]
	Kas, Martien [> >]
	Knapska, Ewelina [> >]
	Koks, Sulev [> >]
	Kolisis, Fragiskos [> >]
	Korostynski, Michal [> >]
	Lammert, Frank [> >]
	Lehrach, Hans [> >]
	Lengeling, Andreas [> >]
	Libert, Claude [> >]
	Montagutelli, Xavier [> >]
	Morahan, Grant [> >]
	Mott, Richard [> >]
	Panthier, Jean-Jacques [> >]
	Przewlocki, Ryszard [> >]
	Ranki, Annamari [> >]
	Santos, Javier [> >]
	Severcan, Feride [> >]
	Schalkwyk, Leonard [> >]
	Schughart, Klaus [> >]
	Smit, August B. [> >]
	Terasmaa, Anton [> >]
	Vasar, Eero [> >]
	Zatloukal, Kurt [> >]
Publication date :	2013
Journal title :	European Journal of Human Genetics
Volume :	21
Issue/season :	11
Pages :	1191-6
Peer reviewed :	Yes (verified by ORBilu)
ISSN :	1018-4813
e-ISSN :	1476-5438
Country :	England
Keywords :	[en] Animals ; Biomedical Research ; Humans ; Mice ; Models, Animal ; Reverse Genetics
Abstract :	[en] Experimental animal models are essential to obtain basic knowledge of the underlying biological mechanisms in human diseases. Here, we review major contributions to biomedical research and discoveries that were obtained in the mouse model by using forward genetics approaches and that provided key insights into the biology of human diseases and paved the way for the development of novel therapeutic approaches.
Research centres :	Luxembourg Centre for Systems Biomedicine (LCSB): Experimental Neurobiology (Balling Group)
Permalink :	http://hdl.handle.net/10993/26639
DOI :	10.1038/ejhg.2013.79

	File(s) associated to this reference
	Fulltext file(s): File Commentary Version Size Access Open access ejhg201379a.pdf Publisher postprint 276.78 kB View/Open

All documents in ORBi^lu are protected by a user license.

 

University of Luxembourg Library |  Feedback |  Legal notices Site Map