| Reference : A locus for radiation-induced gastroschisis on mouse Chromosome 7. |
| Scientific journals : Article | |||
| Life sciences : Genetics & genetic processes | |||
| http://hdl.handle.net/10993/1317 | |||
| A locus for radiation-induced gastroschisis on mouse Chromosome 7. | |
| English | |
| Hillebrandt, S. [> >] | |
| Streffer, C. [> >] | |
| Montagutelli, X. [> >] | |
Balling, Rudi  [> >] | |
| 1998 | |
| Mammalian Genome | |
| 9 | |
| 12 | |
| 995-7 | |
| Yes (verified by ORBilu) | |
| 0938-8990 | |
| 1432-1777 | |
| UNITED STATES | |
| [en] Abdominal Muscles/abnormalities/embryology/radiation effects ; Abnormalities, Radiation-Induced/genetics ; Animals ; Chromosome Mapping ; Chromosomes/genetics ; Crosses, Genetic ; Female ; Fetus/drug effects/metabolism ; Gastroschisis/genetics ; Genetic Markers ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Inbred Strains ; Pregnancy ; X-Rays | |
| [en] Gastroschisis (abdominal wall defects) occurs with a high frequency in the mouse inbred strain HLG compared with C57BL/6J mice. The risk of gastroschisis increases significantly after exposure to irradiation with X-rays during preimplantation development and follows a recessive mode of inheritance for the HLG susceptibility alleles. We have used a backcross strategy and genome-wide microsatellite typing to chromosomally map this trait. A suggestive linkage for a locus responsible for radiation-induced gastroschisis (Rigs1) was found in a region of mouse Chromosome 7. | |
| http://hdl.handle.net/10993/1317 |
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