| Reference : A mouse gene homologous to the Drosophila gene caudal is expressed in epithelial cell... |
| Scientific journals : Article | |||
| Life sciences : Genetics & genetic processes | |||
| http://hdl.handle.net/10993/1256 | |||
| A mouse gene homologous to the Drosophila gene caudal is expressed in epithelial cells from the embryonic intestine. | |
| English | |
| Duprey, P. [> >] | |
| Chowdhury, K. [> >] | |
| Dressler, G. R. [> >] | |
Balling, Rudi  [> >] | |
| Simon, D. [> >] | |
| Guenet, J. L. [> >] | |
| Gruss, P. [> >] | |
| 1988 | |
| Genes and Development | |
| 2 | |
| 12A | |
| 1647-54 | |
| Yes (verified by ORBilu) | |
| 0890-9369 | |
| UNITED STATES | |
| [en] Amino Acid Sequence ; Animals ; Base Sequence ; Blotting, Southern ; Chromosome Mapping ; DNA ; DNA Probes ; Drosophila/genetics ; Electrophoresis, Agar Gel ; Embryonic and Fetal Development ; Genes, Homeobox ; Intestines/cytology/embryology ; Mice ; Molecular Sequence Data ; Sequence Homology, Nucleic Acid ; Species Specificity ; Transcription, Genetic | |
| [en] A mouse gene, Cdx-1, was isolated from an embryonic cDNA library using a Drosophila caudal gene probe. The deduced amino acid sequence of Cdx-1 contains conserved sequence domains along the entire gene, as well as a highly conserved caudal-type homeo box. A structural comparison suggests a common ancestral origin of mouse Cdx-1 and Drosophila caudal. The expression of Cdx-1 during embryogenesis was analyzed by Northern blotting and in situ hybridization. Cdx-1-specific transcripts are localized in the epithelial lining of the intestines beginning at 14 days' gestation. The expression of Cdx-1 in the intestine continues into adulthood, but cannot be detected in any other tissues. The Cdx-1 gene is the first homeo-box-containing gene expressed in cells derived from the embryonic endoderm. | |
| http://hdl.handle.net/10993/1256 |
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