Oxidative and conjugative metabolism of diethylstilbestrol by rabbit preimplantation embryos.

Reference : Oxidative and conjugative metabolism of diethylstilbestrol by rabbit preimplantation ...


	Document type :	Scientific journals : Article
	Discipline(s) :	Life sciences : Genetics & genetic processes
	To cite this reference:	http://hdl.handle.net/10993/1252

Title :	Oxidative and conjugative metabolism of diethylstilbestrol by rabbit preimplantation embryos.
Language :	English
Author, co-author :	Balling, Rudi []
	Haaf, H. [> >]
	Maydl, R. [> >]
	Metzler, M. [> >]
	Beier, H. M. [> >]
Publication date :	1985
Journal title :	Developmental Biology
Volume :	109
Issue/season :	2
Pages :	370-4
Peer reviewed :	Yes (verified by ORBi^lu)
ISSN :	0012-1606
e-ISSN :	1095-564X
Country :	UNITED STATES
Keywords :	[en] Animals ; Biotransformation ; Blastocyst/metabolism ; Diethylstilbestrol/analogs & derivatives/metabolism ; Gestational Age ; Glucuronosyltransferase/metabolism ; Oxygenases/metabolism ; Rabbits ; Sulfurtransferases/metabolism
Abstract :	[en] Five- and six-day-old rabbit preimplantation embryos were found to be capable of metabolizing [3H]diethylstilbestrol (DES) in vitro. Based on the analysis of the metabolites formed during a 24-hr incubation period we conclude that these early stage embryos do have active monooxygenase and conjugative activity. The monooxygenase seems to be specific to this early stage of embryonic development.
Permalink :	http://hdl.handle.net/10993/1252

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