http://hdl.handle.net/10993/143 Search this channel search https://orbilu.uni.lu/simple-search http://hdl.handle.net/10993/53082 Title: Google Scholar: a review of literature examining its effectiveness as a search tool <br/> <br/>Author, co-author: Korjonen, Maria Helena <br/> <br/>Abstract: Google Scholar (GS) is the top search engine used by those who are looking for scholarly content1. There are many reasons for this, not least that it feels familiar 2, 3. However, a review of the literature reveals that there are significant limitations to its effectiveness.   Tue, 13 Dec 2022 09:50:00 GMT http://hdl.handle.net/10993/52129 Title: Microgliosis: a double-edged sword in the control of food intake <br/> <br/>Author, co-author: Salvi, Juliette; Andreoletti, Pierre; Audinat, Etienne; Balland, Eglantine; Ben Fradj, Selma; Cherkaoui-Malki, Mustapha; Heurtaux, Tony; Lienard, Fabienne; Nedelec, Emmanuelle; Rovere, Carole; Savary, Stéphane; Vejux, Anne; Trompier, Doriane; Benani, Alexandre <br/> <br/>Abstract: Maintaining energy balance is essential for survival and health. This physiological function is controlled by the brain, which adapts food intake to energy needs. Indeed, the brain constantly receives a multitude of biological signals that are derived from digested foods or that originate from the gastrointestinal tract, energy stores (liver and adipose tissues) and other metabolically active organs (muscles). These signals, which include circulating nutrients, hormones and neuronal inputs from the periphery, collectively provide information on the overall energy status of the body. In the brain, several neuronal populations can specifically detect these signals. Nutrient-sensing neurons are found in discrete brain areas and are highly enriched in the hypothalamus. In turn, specialized brain circuits coordinate homeostatic responses acting mainly on appetite, peripheral metabolism, activity and arousal. Accumulating evidence shows that hypothalamic microglial cells located at the vicinity of these circuits can influence the brain control of energy balance. However, microglial cells could have opposite effects on energy balance, that is homeostatic or detrimental, and the conditions for this shift are not totally understood yet. One hypothesis relies on the extent of microglial activation, and nutritional lipids can considerably change it. Tue, 20 Sep 2022 14:45:38 GMT http://hdl.handle.net/10993/41870 Title: Banana starch nanocomposite with cellulose nanofibers isolated from banana peel by enzymatic treatment: In vitro cytotoxicity assessment <br/> <br/>Author, co-author: Tibolla, H.; Pelissari, F. M.; Martins, J. T.; Martin Lanzoni, Evandro; Vicente, A. A.; Menegalli, F. C.; Cunha, R. L. <br/> <br/>Abstract: The potential use of cellulose nanofibers (CNFs) as a reinforcing agent in banana starch-based nanocomposite films was investigated. CNFs were isolated from banana peel (Musa paradisiaca) by enzymatic hydrolysis. Banana starch-based nanocomposite films were prepared with CNFs using the casting method. CNFs effect on cell viability and on nanocomposite films properties’ was investigated. The cytotoxicity of CNFs was assessed on Caco-2 cell line. CNFs were not cytotoxic at 50–2000 μg/mL. However, CNFs above 2000 μg/mL significantly decreased cell viability. Topography analysis showed that the incorporation of CNFs modified the film structure. The nanocomposites exhibited a complex structure due to strong interactions between CNFs and starch matrix, promoting a remarkable improvement on mechanical and water barrier properties, opacity and UV light barrier compared to the control film. CNFs can offer a great potential as reinforcing material for starch-based nanocomposite films, producing a value-added food packaging from a waste material. Wed, 22 Jan 2020 08:34:20 GMT http://hdl.handle.net/10993/36963 Title: Presentation: "Mesophilic and Thermophilic Anaerobic Digestion of Model Kitchen Waste with Variation of Fat Content" <br/> <br/>Author, co-author: Sobon-Muehlenbrock, Elena; Greger, Manfred; Schlienz, Markus Wed, 17 Oct 2018 08:45:19 GMT http://hdl.handle.net/10993/22500 Title: A low protein diet during early gestation in sheep detrimentally impacts hepatic glucose metabolism in the adult offspring <br/> <br/>Author, co-author: Gardner, David S.; Rhodes, Phillip; Karamitri, Angeliki; Glaab, Enrico; Rhind, Stuart M. <br/> <br/>Abstract: Differences in maternal diet can account for variation in the metabolic competence of the subsequent individual as an adult. ‘Developmental programming’ may impair fetal organ development leading to a limitation in function as an adult and/or increase the rate of age-related organ decline for example under conditions of obesity. Here, we have tested the interaction between prenatal nutritional ‘thrift’ and postnatal nutritional excess on gluco-regulatory functions in an ovine model. Seventy-four Scottish Blackface ewes were randomly assigned to receive either a control protein diet with adequate energy (18% protein; CP, n 20) or low protein diet (9% protein) fed during early gestation (0–65 d, term ~147 d; LPE, n 37) or late gestation (65–147 d; LPL, n 17). At 65 d a proportion of ewes was euthanised for fetal sampling. At term, remaining ewes lambed naturally, were weaned at 10 weeks and a random sample of offspring studied longitudinally when lean (1.5 years of age) and after 6 months exposure to an obesogenic environment. Body composition was determined by dual-energy absorptiometry and glucose and insulin tolerance tests were conducted with appropriate sampling intervals. At post mortem, muscle and hepatic tissues were sampled for expression and abundance of relevant gluco-regulatory genes. The diets had little effect on maternal weight and body composition through gestation or on fetal weights at 65 d. Term weight was reduced by ~500 g (P = 0.001) in LPL v. other groups but, by weaning, body weight was similar between groups and growth rate to adulthood was not different. Homeostasis model assessment of baseline glucose and insulin concentrations indicated relative insulin resistance in male LPE . Indeed, when challenged with a GTT, the incremental insulin AUC was significantly greater in male LPE when obese but not when lean (unpublished results). Molecular quantification of glucose-insulin pathways in muscle and liver indicated specific down-regulation of the hepatic insulin, but not lipid, pathways in male liver only. Muscle insulin-signalling pathways were unaffected as determined by microarray (Affymetrix, U133 chip; www.arraymining.net). The data suggest that a maternal, low protein, diet during early gestation specifically impacts upon the function of the resulting adult liver, such that the offspring appear more susceptible to large excursions in plasma insulin during gluco-regulatory challenges. The insulin sensitivity of offspring muscle, the largest single source of insulin-stimulated glucose uptake, was largely unaffected. Thus, obesity appears to exacerbate any functional deficits inherent in low protein exposed offspring in sheep, but those offspring born of low birth weight were largely unaffected, illustrating that nutritional quality is far more important than nutritional quantity especially during sensitive developmental phases of growth. Wed, 18 Nov 2015 10:15:22 GMT http://hdl.handle.net/10993/21239 Title: Democratizing Decision-Making on Food-Safety in the E.U.: Closing gaps between principles of governance and practice <br/> <br/>Author, co-author: König, Ariane <br/> <br/>Abstract: Food safety is a preoccupation of the European Commission, but there are major shortcomings in its governance. Reviewing legislation and practice, this paper explores the background of EU food safety institutions, and develops recommendations to make the EU decision process more transparent, accountable, and democratic. Fri, 05 Jun 2015 07:48:11 GMT http://hdl.handle.net/10993/12409 Title: Genetically modified crops in the EU: Food safety assessment, regulation and public concerns. Project report for ENTRANSFOOD, the European network on safety assessment of genetically modified crops. <br/> <br/>Author, co-author: König, Ariane; Kleter, Gijs; Hammes, Walter; Knudsen, Ib; Kuiper, Harry Mon, 02 Dec 2013 12:41:25 GMT http://hdl.handle.net/10993/12404 Title: A quantitative analysis of fish consumption and stroke risk. <br/> <br/>Author, co-author: Bouzan, C.; Cohen, J. T.; Connor, W. E.; Kris-Etherton, P. M.; Gray, G. M.; König, Ariane; Lawrence, R. S.; Savitz, D. A.; Teutsch, S. M. <br/> <br/>Abstract: Although a rich source of n-3 polyunsaturated fatty acids (PUFAs) that may confer multiple health benefits, some fish contain methyl mercury (MeHg), which may harm the developing fetus. U.S. government recommendations for women of childbearing age are to modify consumption of high-MeHg fish to reduce MeHg exposure, while recommendations encourage fish consumption among the general population because of the nutritional benefits. The Harvard Center for Risk Analysis convened an expert panel (see acknowledgements) to quantify the net impact of resulting hypothetical changes in fish consumption across the population. This paper estimates the impact of fish consumption on stroke risk. Other papers quantify coronary heart disease mortality risk and the impacts of both prenatal MeHg exposure and maternal intake of n-3 PUFAs on cognitive development. This analysis identified articles in a recent qualitative literature review that are appropriate for the development of a dose-response relationship between fish consumption and stroke risk. Studies had to satisfy quality criteria, quantify fish intake, and report the precision of the relative risk estimates. The analysis combined the relative risk results, weighting each proportionately to its precision. Six studies were identified as appropriate for inclusion in this analysis, including five prospective cohort studies and one case-control study (total of 24 exposure groups). Our analysis indicates that any fish consumption confers substantial relative risk reduction compared to no fish consumption (12% for the linear model), with the possibility that additional consumption confers incremental benefits (central estimate of 2.0% per serving per week). Mon, 02 Dec 2013 11:49:30 GMT http://hdl.handle.net/10993/1285 Title: Initial steps of myogenesis in somites are independent of influence from axial structures. <br/> <br/>Author, co-author: Bober, E.; Brand-Saberi, B.; Ebensperger, C.; Wilting, J.; Balling, Rudi; Paterson, B. M.; Arnold, H. H.; Christ, B. <br/> <br/>Abstract: Formation of paraxial muscles in vertebrate embryos depends upon interactions between early somites and the neural tube and notochord. Removal of both axial structures results in a complete loss of epaxial myotomal muscle, whereas hypaxial and limb muscles develop normally. We report that chicken embryos, after surgical removal of the neural tube at the level of the unsegmented paraxial mesoderm, start to develop myotomal cells that express transcripts for the muscle-specific regulators MyoD and myogenin. These cells also make desmin, indicating that the initial steps of axial skeletal muscle formation can occur in the absence of the neural tube. However, a few days following the extirpation, the expression of MyoD and myogenin transcripts gradually disappears, and becomes almost undetectable after 4 days. From these observations we conclude that the neural tube is not required for the generation of the skeletal muscle cell lineage, but may support the survival or maitenance of further differentiation of the myotomal cell compartment. Notochord transplanted medially or laterally to the unsegmented paraxial mesoderm leads to a ventralization of axial structures but does not entirely prevent the early appearance of myoblasts expressing MyoD transcripts. However, the additional notochord inhibits subsequent development and maturation of myotomes. Taken together, our data suggest that neural tube promotes, and notochord inhibits, the process of myogenesis in axial muscles at a developmental step following the initial expression of myogenic bHLH regulators. Fri, 10 May 2013 13:26:57 GMT