A CutFEM Method for a spatial resolved energy metabolism model in complex cellular geometries

Scientific Conference (2021, January)

Computational techniques have been widely used to tackle problems in the biological sciences. A com- promise between high quality simulations and simple but accurate models can help to understand un ... [more ▼]

Computational techniques have been widely used to tackle problems in the biological sciences. A com- promise between high quality simulations and simple but accurate models can help to understand un- known aspects of this field. In this work, we will show how the Cut Finite Element Method (CutFEM) [1] can be a powerful tool to solve a reaction diffusion PDE system that models the energy metabolism of a cell. The main difficulty to approach this problem is dealing with the morphology of the cell that can have sharp edges and evolves over time. While classical FEM requires the mesh conform to the domain boundary, CutFEM allows a non-conforming discretisation of the domain, and thus is especially suited for modeling complex and evolving cellular geometries. First, we introduce our simplified model for metabolic pathways taking place in a region small enough to consider the material property as homogeneous. The results obtained with FEM (FENICS Project [2][3]) and CutFEM suggest that the two methods are equivalent. This allows us to use CutFEM to increase the complexity of the domain, from a spherical shaped cell to an irregular astrocyte. We conclude that CutFEM is a robust method for tackling biological problems with complex geometries, opening the possibility to extend the complexity of our mathematical model including more features and to consider real cellular shapes that evolve in time in future work. [less ▲]

Cu–Zn disorder and band gap fluctuations in Cu2ZnSn(S,Se)4: Theoretical and experimental investigations

in Physica Status Solidi B. Basic Research (2016), 253(2), 247-254

Le Cvce.eu, une infrastructure numérique

Presentation (2017, December 18)

Présentation des publications numériques sur le processus de la construction européenne analysé dans une perspective transnationale et multidimensionnelle sur le site cvce.eu. Les collections de ... [more ▼]

Présentation des publications numériques sur le processus de la construction européenne analysé dans une perspective transnationale et multidimensionnelle sur le site cvce.eu. Les collections de publications thématiques et le programme d’histoire orale, comprenant près de 100 interviews de personnalités européennes, constituent une approche innovante de la construction européenne. [less ▲]

Cyber bullying among school aged children in Luxembourg

Scientific Conference (2009, August)

Cyber bullying: Current research findings

Scientific Conference (2009, April)

Cyber bullying: The role of traditional bullying and empathy

in Sapeo, B.; Haddon, L.; Mante-Meijer, E. (Eds.) et al The good, the bad and the challenging. Conference Proceedings (Vol. II) (2009)

Cyber Security and Vulnerability Analysis of Networked Control System subject to False-Data injection

in Proceedings of the 2018 American Control Conference (2018, June 27)

In the present paper, the problem of networked control system (NCS) cyber security is considered. The geometric approach is used to evaluate the security and vulnerability level of the controlled system ... [more ▼]

In the present paper, the problem of networked control system (NCS) cyber security is considered. The geometric approach is used to evaluate the security and vulnerability level of the controlled system. The proposed results are about the so-called false data injection attacks and show how imperfectly known disturbances can be used to perform undetectable, or at least stealthy, attacks that can make the NCS vulnerable to attacks from malicious outsiders. A numerical example is given to illustrate the approach. [less ▲]

Cyberbullying as an act of revenge?

in Australian Journal of Guidance & Counselling (2010), 20(2), 210-224

Despite significant overlaps between victim status in traditional forms of bullying and cyberbullying, and qualitative results about self-reported reasons for cyberbullying, the role of revenge and ... [more ▼]

Despite significant overlaps between victim status in traditional forms of bullying and cyberbullying, and qualitative results about self-reported reasons for cyberbullying, the role of revenge and retaliation as a motive to engage in acts of cyberbullying has not yet been examined systematically. As a first step, this study investigates whether and to what extent traditional victims, when they become cyberbullies, actually choose their former (traditional) perpetrators as targets of their own cyberbullying behavior. Furthermore, the impact of individual differences in relevant traits, such as vengefulness and justice sensitivity, on the choice of cybervictims is examined. Data from 473 students were collected via an online survey. Of these, 149 were identified as traditional victims/cyberbullies. Results show that traditionally bullied students indeed tend to choose their former perpetrators as cybervictims, and that individual differences play a role in the choice of their victims. Implications for further research, as well as for interventions and prevention programmes, are discussed. [less ▲]

Cyberbullying through the new media: Findings from an international network

Book published by Psychology Press (2013)

Cyberbullying: Missbrauch mittels neuer elektronischer Medien

in Willems, Helmut; Ferring, Dieter (Eds.) Macht und Missbrauch in Institutionen (2014)