Ownership Concentration, Institutional Development and Firm Performance in Central and Eastern Europe

in Managerial and Decision Economics (2017), 38

Ownership of Satellites: A Simple Legal Fact with Complex Consequences

in Hofmann, Mahulena; Loukakis, Andreas (Eds.) Ownership of Satellites (2017)

International space law does not always connect the obligation and rights of States Parties with the ownership of the satellite. However, the transfer of ownership is a relatively frequent phenomenon. The ... [more ▼]

International space law does not always connect the obligation and rights of States Parties with the ownership of the satellite. However, the transfer of ownership is a relatively frequent phenomenon. The main problem may occur if the satellite is sold in one of the non-launching States. The article analyses various scenarios and suggested solutions. [less ▲]

Oxatomide and calcium: mechanisms involved in the secretion of mast cell mediators

in Annales de Dermatologie et de Vénéréologie (1990), 117 Suppl 1

Human cutaneous mast cells and their experimental model rat peritoneal mast cells, can be stimulated by an IgE-dependent process or by peptides through the direct activation of G proteins. Both activation ... [more ▼]

Human cutaneous mast cells and their experimental model rat peritoneal mast cells, can be stimulated by an IgE-dependent process or by peptides through the direct activation of G proteins. Both activation pathways lead to the increase of cytosolic Ca2+ level. This increase in dependent of the mobilisation of intracellular calcium stores of the endoplasmic reticulum involving the stimulation of IP3-sensitive calcium channels. Mast cells are characterized by the absence of calcium channels in the plasma membrane. Oxatomide has been synthetized as an analog of cinnarizine. However oxatomide is inactive on current calcium channels. In mast cells, oxatomide inhibits the increase of cytosolic calcium elicited during mast cell activation. Consequently mast cell exocytosis is inhibited altogether with the release of newly synthetized mediators. The authors propose several putative targets for oxatomide in mast cells. The therapeutic effect of oxatomide is also related to its property to antagonize the effects of anaphylactic mediators on their selective receptors. [less ▲]

Oxidation as Key Mechanism for Efficient Interface Passivation in Cu(In,Ga)Se2 Thin-Film Solar Cells

in Physical Review Applied (2020)

Oxidative stress activates MMP-2 in cultured human coronary smooth muscle cells

in Fundamental and Clinical Pharmacology (2005), 19(6), 661-7

Oxidative stress is a cardinal feature of the inflammatory process and is involved in various pathologies including atherosclerosis. One of the important mechanisms in which oxidative stress may play a ... [more ▼]

Oxidative stress is a cardinal feature of the inflammatory process and is involved in various pathologies including atherosclerosis. One of the important mechanisms in which oxidative stress may play a role is activation of matrix metalloproteinases such as MMP-2, which are involved in plaque destabilization. We investigated the mechanisms by which oxidative stress induces MMP-2 activation in cultured human coronary artery smooth muscle cells. Using zymography and Western blot analysis, we showed that oxidized low-density lipoproteins activate MMP-2 through up-regulation of the expression and activation of a membrane-type 1 matrix metalloproteinase (MT1-MMP). A second mechanism of MMP-2 activation involves oxidative radicals generated by the xanthine/xanthine oxidase complex (X/Xo). Research on these two mechanisms of MMP activation could lead to the elaboration of new vascular therapies for the treatment of atheroma based on interruption of a specific oxidative stress pathway. [less ▲]

Oxytocin administration and emotion recognition abilities in adults with a history of childhood adversity

in Psychoneuroendocrinology (2019), 99

Oxytocin and the stress buffering effect of social company: A genetic study in daily life

in Social Cognitive and Affective Neuroscience (2020), 15(3), 293-301

Oxytocin, stress and social behavior: Neurogenetics of the human oxytocin system

in Current Opinion in Neurobiology (2013), 23(1), 11-16

p15 promoter methylation - A novel prognostic marker in glioblastoma patients

in International Journal of Oncology (2009), 34(6), 1743-48

P2P Marketplaces and Retailing in the Presence of Consumers' Valuation Uncertainty

in Production and Operations Management (2017), 26(3), 509--524