References of "2021"
     in
Bookmark and Share    
See detailTrauer an Schulen. Basiswissen und Hinweise zum Umgang mit Sterben und Tod
Böhmer, Matthias UL; Steffgen, Georges UL

Book published by Springer (2021)

Detailed reference viewed: 24 (0 UL)
Full Text
See detailExplaining Defect Detection with Saliency Maps
Lorentz, Joe UL; Hartmann, Thomas; Moawad, Assaad et al

E-print/Working paper (2021)

The rising quality and throughput demands of the manufacturing domain require flexible, accurate and explainable computer-vision solutions for defect detection. Deep Neural Networks (DNNs) reach state-of ... [more ▼]

The rising quality and throughput demands of the manufacturing domain require flexible, accurate and explainable computer-vision solutions for defect detection. Deep Neural Networks (DNNs) reach state-of-the-art performance on various computer-vision tasks but wide-spread application in the industrial domain is blocked by the lacking explainability of DNN decisions. A promising, human-readable solution is given by saliency maps, heatmaps highlighting the image areas that influence the classifier’s decision. This work evaluates a selection of saliency methods in the area of industrial quality assurance. To this end we propose the distance pointing game, a new metric to quantify the meaningfulness of saliency maps for defect detection. We provide steps to prepare a publicly available dataset on defective steel plates for the proposed metric. Additionally, the computational complexity is investigated to determine which methods could be integrated on industrial edge devices. Our results show that DeepLift, GradCAM and GradCAM++ outperform the alternatives while the computational cost is feasible for real time applications even on edge devices. This indicates that the respective methods could be used as an additional, autonomous post-classification step to explain decisions taken by intelligent quality assurance systems. [less ▲]

Detailed reference viewed: 42 (0 UL)
See detailComprehensive peptidomic analysis of cell culture models and exosomes
Fougeras, Miriam Rebecca UL

Doctoral thesis (2021)

Cellular endogenous peptides may harbour important signalling functions regulating health and disease. The identification of functional peptides by mass spectrometry is very challenging but it allows ... [more ▼]

Cellular endogenous peptides may harbour important signalling functions regulating health and disease. The identification of functional peptides by mass spectrometry is very challenging but it allows identification and quantification of peptides in a large-scale and can provide experimental evidence of bioactive peptides. Quantitative approaches can provide insights in the regulation of endogenous peptides, however, they need a robust peptide extraction methodology. We demonstrated that different approaches for peptidomic sample preparation introduce variation and strongly influence the identification of different sets of peptides, showing the need of a critical evaluation of peptide extraction protocols. We identified a global peptidome, stable throughout different cell lines and within different organisms. And high numbers of identification allows us to target cellular fractions. An interesting source of bioactive peptides are extracellular vesicles (EVs). EVs transfer signalling molecules for cell-to-cell communication with surrounding but also distant cells. In cancer, EVs are involved in tumour progression, metastasis and treatment resistance. Their purity for proteomic and peptidomic analysis is very crucial and we consequently described strategies to assess the vesicle purity by mass spectrometry and selected a robust sample preparation method for further application. We identified many nuclear proteins enriched in EVs upon hypoxic treatment, even though general cellular markers were overall highly reduced in EV samples compared to cell samples. We thus conclude that the enriched cargo of the EVs is the result of targeted exocytosis of important proteins for tumour progression, rather than random co-exportation. An increased export of nuclear proteins involved in DNA replication, repair or chromatin remodelling suggests a proliferation-related signature of hypoxic EVs. So far, most EV studies are limited to the EVs’ nucleic acid, lipid or proteomic cargo, but little is known about the peptidomic cargo. Challenges of EV peptidomics lie in the low starting material EVs provide, compared to the high starting material which is usually needed for peptidomic studies. However, the exploitation of EVs regarding their peptidomic cargo might pave the way for better understanding of signalling pathways. Thus we aimed at comprehensively studying the cellular and EV peptidome. By combining different peptide extraction methodologies, we detected a vesicle- and a cell-origin related signature in the peptidome and we showed the feasibility of a parallel peptide and protein extraction and it’s advantage for precious EV-enriched samples. [less ▲]

Detailed reference viewed: 27 (2 UL)
See detailDe la naissance de l’État luxembourgeois. Analyse et historique de la problématique
Heuschling, Luc UL

in Actes de la section des sciences morales et politiques de l'Institut grand-ducal (2021), Vol XXIV

Detailed reference viewed: 49 (2 UL)
Full Text
Peer Reviewed
See detailTests and estimation strategies associated to some loss functions
Baraud, Yannick UL

in Probability Theory and Related Fields (2021), 180(3), 799-846

We consider the problem of estimating the joint distribution of n independent random variables. Given a loss function and a family of candidate probabilities, that we shall call a model, we aim at ... [more ▼]

We consider the problem of estimating the joint distribution of n independent random variables. Given a loss function and a family of candidate probabilities, that we shall call a model, we aim at designing an estimator with values in our model that possesses good estimation properties not only when the distribution of the data belongs to the model but also when it lies close enough to it. The losses we have in mind are the total variation, Hellinger, Wasserstein and L_p-distances to name a few. We show that the risk of our estimator can be bounded by the sum of an approximation term that accounts for the loss between the true distribution and the model and a complexity term that corresponds to the bound we would get if this distribution did belong to the model. Our results hold under mild assumptions on the true distribution of the data and are based on exponential deviation inequalities that are non-asymptotic and involve explicit constants. Interestingly, when the model reduces to two distinct probabilities, our procedure results in a robust test whose errors of first and second kinds only depend on the losses between the true distribution and the two tested probabilities. [less ▲]

Detailed reference viewed: 191 (43 UL)
Full Text
See detailMachine learning in the social and health sciences
Leist, Anja UL; Klee, Matthias UL; Kim, Jung Hyun UL et al

E-print/Working paper (2021)

The uptake of machine learning (ML) approaches in the social and health sciences has been rather slow, and research using ML for social and health research questions remains fragmented. This may be due to ... [more ▼]

The uptake of machine learning (ML) approaches in the social and health sciences has been rather slow, and research using ML for social and health research questions remains fragmented. This may be due to the separate development of research in the computational/data versus social and health sciences as well as a lack of accessible overviews and adequate training in ML techniques for non data science researchers. This paper provides a meta-mapping of research questions in the social and health sciences to appropriate ML approaches, by incorporating the necessary requirements to statistical analysis in these disciplines. We map the established classification into description, prediction, and causal inference to common research goals, such as estimating prevalence of adverse health or social outcomes, predicting the risk of an event, and identifying risk factors or causes of adverse outcomes. This meta-mapping aims at overcoming disciplinary barriers and starting a fluid dialogue between researchers from the social and health sciences and methodologically trained researchers. Such mapping may also help to fully exploit the benefits of ML while considering domain-specific aspects relevant to the social and health sciences, and hopefully contribute to the acceleration of the uptake of ML applications to advance both basic and applied social and health sciences research. [less ▲]

Detailed reference viewed: 47 (0 UL)
Full Text
See detailEuropean Border Region Studies in Times of Borderization
Wille, Christian UL

E-print/Working paper (2021)

The text originates from a time of borderization, at global level and at the EU’s internal borders. At the latest since covidfencing began in the spring of 2020, many Europeans have become familiar with ... [more ▼]

The text originates from a time of borderization, at global level and at the EU’s internal borders. At the latest since covidfencing began in the spring of 2020, many Europeans have become familiar with border experiences and the practices of civic contestation of borders. With that in mind, the text argues that it is necessary to open European border region studies to the contestation of borders, for which it should enter into dialogue with international (and critical) border studies. [less ▲]

Detailed reference viewed: 81 (3 UL)
See detailIntergenerational Family Solidarity across Europe
Albert, Isabelle UL; Emirhafizovic, Mirza; Shpigelman, Carmit-Noa et al

in Albert, Isabelle; Emirhafizovic, Mirza; Shpigelman, Carmit-Noa (Eds.) et al Families and family values in society and culture (2021)

The global trend of ageing populations is particularly pronounced in Europe. In the wake of increased life expectancies, intergenerational family relationships have become more and more important over the ... [more ▼]

The global trend of ageing populations is particularly pronounced in Europe. In the wake of increased life expectancies, intergenerational family relationships have become more and more important over the last few decades. The COST Action INTERFASOL started from the claim that in light of these developments societies need to develop mechanisms, programs and policies that will support solidarity between the young, middle and older generations. Although considerable research activities in the field of intergenerational relations have been carried out in the last years, a lack in coordination and integration of different studies from different settings was noted. Bringing together research from different countries to coordinate studies and synthesize results is not an easy endeavor but it has turned out as a fruitful venture: INTERFASOL has been successful in bringing together researchers from 28 different countries meeting regularly, discussing current issues and not least producing a large number of publications and research proposals. One outcome of the COST Action is this volume which has the aim to become a reference for all those who are interested in intergenerational relations in Europe: the chapters will provide the basis and a starting point for further research. [less ▲]

Detailed reference viewed: 20 (0 UL)
Full Text
Peer Reviewed
See detailLimit theorems for integral functionals of Hermite-driven processes
Garino, Valentin UL; Nourdin, Ivan UL; Nualart, David et al

in Bernoulli (2021), 27(3), 1764-1788

Detailed reference viewed: 75 (12 UL)
See detailFamilies and family values in society and culture
Albert, Isabelle UL; Emirhafizovic, Mirza; Shpigelman, Carmit-Noa et al

Book published by Information Age Publishing (2021)

This book which has been created in the framework of the EU-funded COST Action INTERFASOL brings together researchers from 22 INTERFASOL countries, who frame intergenerational family solidarity in the ... [more ▼]

This book which has been created in the framework of the EU-funded COST Action INTERFASOL brings together researchers from 22 INTERFASOL countries, who frame intergenerational family solidarity in the specific historical, cultural, social and economic context of their own country. Integrating different perspectives from social and political sciences, economics, communication, health and psychology, the book offers country-specific knowledge and new insights into family relations, family values and family policies across Europe. The volume is the product of a unique endeavor of researchers across Europe to provide up-to-date first-hand country-specific knowledge on family and intergenerational relations and will serve as a base for both country-specific as well as cross-cultural studies. [less ▲]

Detailed reference viewed: 75 (1 UL)
See detailFamilies Across Europe - Now and Then
Albert, Isabelle UL; Valsiner, Jaan; Komatsu, Koji

in Albert, Isabelle; Emirhafizovic, Mirza; Shpigelman, Carmit-Noa (Eds.) et al Families and Family Values in Society and Culture (2021)

Detailed reference viewed: 86 (0 UL)
Full Text
Peer Reviewed
See detailSmarter charging: Power allocation accounting for travel time of electric vehicle drivers
Fridgen, Gilbert UL; Thimmel, Markus; Weibelzahl, Martin et al

in Transportation Research Part D: Transport and Environment (2021), 97

Growing electric vehicle (EV) dissemination will increase charging infrastructure installation at home. Similar daily routines are associated with high peak loads due to simultaneous EV charging. However ... [more ▼]

Growing electric vehicle (EV) dissemination will increase charging infrastructure installation at home. Similar daily routines are associated with high peak loads due to simultaneous EV charging. However, predominantly residential power transmission is not designed for such high loads, yielding charging bottlenecks and restricting future charging at home. Addressing such bottleneck situations and including the EV driver perspective, we introduce a power allocation mechanism that considers the total travel time of the upcoming trip, consisting of actual driving time and time required for charging externally (including the detour to public charging facilities). Assuming that travel time generally negatively correlates with EV driver utility, our optimization model maximizes the resulting utility of EV drivers. Avoiding unnecessary external charging stops due to an insufficient state of charge at the time of departure, our approach generates travel time savings that increase overall EV driver utility. We illustrate our approach using exemplary cases. [less ▲]

Detailed reference viewed: 76 (0 UL)
Full Text
Peer Reviewed
See detailADS-B Signal Detection via Time-Frequency Analysis for Radio Astronomy Applications
Silva, Felipe B.; Cetin, Ediz; Alves Martins, Wallace UL

in IEEE International Symposium on Circuits and Systems (ISCAS), Daegu 22-28 May 2021 (2021)

This paper proposes a time-frequency (TF) domain technique for detecting the presence of automatic dependent surveillance-broadcast (ADS-B) interference signals in radio astronomy applications. The ... [more ▼]

This paper proposes a time-frequency (TF) domain technique for detecting the presence of automatic dependent surveillance-broadcast (ADS-B) interference signals in radio astronomy applications. The proposed technique uses a priori knowledge about the ADS-B signal’s frequency information and compares it with the received signal’s spectrogram time slices via the cosine similarity function. In the presence of ADS-B signals, the similarity levels are higher, whereas in their absence the levels are lower. Hence, the proposed approach exploits this to detect the presence of such signals. Simulation results using signals from the Parkes radio telescope show the efficacy of the proposed method in detecting the presence of ADS-B signals when compared with other classic detectors. [less ▲]

Detailed reference viewed: 28 (0 UL)
Full Text
Peer Reviewed
See detailRecent advances on plasmonic nanocavities for single-molecule spectroscopy
Maccaferri, Nicolò UL; Barbillon, Grégory; Koya, Alemayehu Nana et al

in Nanoscale Advances (2021), 3

Plasmonic nanocavities are able to engineer and confine electromagnetic fields into subwavelength volumes. In the past decade, they have enabled a large set of applications, in particular for sensing ... [more ▼]

Plasmonic nanocavities are able to engineer and confine electromagnetic fields into subwavelength volumes. In the past decade, they have enabled a large set of applications, in particular for sensing, optical trapping, as well as the investigation of physical and chemical phenomena at a few or single-molecule levels. This extreme sensitivity is possible thanks to the highly confined local field intensity enhancement, which depends on the geometry of the plasmonic nanocavities. Indeed, properly designed structures providing engineered local optical fields lead to enhanced optical sensing based on different phenomena like surface enhanced Raman scattering, fluorescence, and Förster Resonant Energy Transfer. In this mini-review, we illustrate the most recent results on plasmonic nanocavities, with specific emphasis on the detection of single molecules. [less ▲]

Detailed reference viewed: 135 (23 UL)
Full Text
Peer Reviewed
See detailDisentangling Inclusion in Physical Education Lessons: Developing a Resource Toolkit for Teachers
Scheuer, Claude UL; Boot, Erik; Carse, Nicola et al

in Balint, Gheorghe; Antala, Branislav; Carty, Catherine (Eds.) et al Physical Education and Sport for Children and Youth with Special Needs Researches – Best Practices – Situation (2021)

The practices adopted by physical education teachers are critical to the success of true inclusion policies. The Disentangling inclusion in primary physical education project aims to fill the existing gap ... [more ▼]

The practices adopted by physical education teachers are critical to the success of true inclusion policies. The Disentangling inclusion in primary physical education project aims to fill the existing gap of information and resources related to inclusion in primary physical education in one specific platform. As a starting point, a literature review and an online survey were undertaken to map the current situation regarding inclusive primary physical education. Based on their results and the recommendations derived from there, a free open educational resource in the form of a web application, focused on highlighting inclusive physical education strategies, has been developed. It is composed of different thematic modules (e.g. chronic conditions or sensory) highlighting the skills learners possess and challenges they may experience as they access the physical education curriculum. By using the resource, it is expected that a large number of teachers and student teachers will be enabled to diversify their pedagogies in issues related to inclusion in primary physical education. As a further consequence, their pedagogical skills and competences shall be enhanced. [less ▲]

Detailed reference viewed: 67 (4 UL)
Full Text
Peer Reviewed
See detailSocial classroom climate and personalised instruction as predictors of students’ social participation
Zurbriggen, Carmen UL; Hofmann, Verena; Lehofer, Mike et al

in International Journal of Inclusive Education (2021)

Previous research has repeatedly confirmed that students with special educational needs (SEN) are generally less accepted by their peers. Although inclusive teaching strategies and classroom ... [more ▼]

Previous research has repeatedly confirmed that students with special educational needs (SEN) are generally less accepted by their peers. Although inclusive teaching strategies and classroom characteristics are frequently hypothesised to improve students’ social participation, empirical evidence is scarce. Therefore, the purpose of this paper is to investigate classroom characteristics and teaching practices that can help foster social participation, in general, and reduce the effect of lower social participation among students with SEN, in particular. The sample includes 518 students in 31 Grade 4 and 7 classes from Austria, of whom 99 are students with SEN. The results show that students with SEN receive fewer peer nominations and perceive their social participation to be lower compared to their peers without SEN. However, the association between SEN and self-perceived social participation is moderated by the social classroom climate, i.e. the difference becomes smaller when the social classroom climate is more positive. Furthermore, the higher the personalised instruction was rated by a student, the higher was his or her social status. The results suggest that interventions should focus not only on the improvement of individual students (with SEN) but also on changing the whole classroom environment. [less ▲]

Detailed reference viewed: 53 (5 UL)