An exploratory approach for an oriented development of an untargeted hydrophilic interaction liquid chromatography-mass spectrometry platform for polar metabolites in biological matrices; ; Talavera Andujar, Begona et alin Journal of Chromatography. A (2020) The analysis of polar metabolites based on liquid chromatography-mass spectrometry (LC-MS) methods should take into consideration the complexity of interactions in LC columns to be able to cover a broad ... [more ▼] The analysis of polar metabolites based on liquid chromatography-mass spectrometry (LC-MS) methods should take into consideration the complexity of interactions in LC columns to be able to cover a broad range of metabolites of key biological pathways. Therefore, in this study, different chromatographic columns were tested for polar metabolites including reversed-phase and hydrophilic interaction liquid chromatography (HILIC) columns. Based on a column screening, two new generations of zwitterionic HILIC columns were selected for further evaluation. A tree-based method optimization was applied to investigate the chromatographic factors affecting the retention mechanisms of polar metabolites with zwitterionic stationary phases. The results were evaluated based on a scoring system which was applied for more than 80 polar metabolites with a high coverage of key human metabolic pathways. The final optimized methods showed high complementarity to analyze a wide range of metabolic classes including amino acids, small peptides, sugars, amino sugars, phosphorylated sugars, organic acids, nucleobases, nucleosides, nucleotides and acylcarnitines. Optimized methods were applied to analyze different biological matrices, including human urine, plasma and liver cell extracts using an untargeted approach. The number of high-quality features ( < 30% median relative standard deviation) ranged from 3,755 for urine to 5,402 for the intracellular metabolome of liver cells, showing the potential of the methods for untargeted purposes. [less ▲] Detailed reference viewed: 26 (3 UL) Luxembourger in the USSR: Tambow in Wort und Schrift. Zur logotherapeutischen Funktion von Ego-Dokumenten und Lagerliteratur der Zwangsrekrutierten in sowjetischer GefangenschaftGanschow, Inna ![]() Article for general public (2020) Luxembourg camp literature has its literary roots in the literature of prisoners of war and prisoners of war of the First World War. During their Soviet imprisonment from 1943 to 1953, the Luxembourg ... [more ▼] Luxembourg camp literature has its literary roots in the literature of prisoners of war and prisoners of war of the First World War. During their Soviet imprisonment from 1943 to 1953, the Luxembourg conscripts continued a tradition of documentarism that did not want to create fictional narrative worlds, but instead focused exclusively on what they had experienced themselves. A large part of the texts left behind is also not literature that was written for a larger audience. They have often been published by the authors themselves. Autobiographies, memoirs and a few volumes of poetry (Faber, Bausch, Schauss) were published, some decades later. A fictional play by the former prisoner of war Joseph Schmit has not been printed to this day. Numerous ego documents, as the research of contemporary history calls them today, have also been preserved - private, handwritten texts of a personal nature. Such material will be the primary focus of this paper. The range of Luxembourgish texts to be examined from the Soviet camp ranges from smuggled notes and letters that released comrades brought to Luxembourg, through diaries, speeches and self-made dictionaries to poems and stories, some of which were in the camp and some immediately after their return Tambov and other Soviet camps emerged. [less ▲] Detailed reference viewed: 27 (3 UL) Les anciens légionnaires et la protection sociale au Luxembourg. Une approche transnationaleVenken, Machteld ![]() in Camarda, Sandra; Reinert, Francoise; Sauer, Arnaud (Eds.) et al Légionnaires. Parcours de guerre et de migrations entre le Luxembourg et la France. (2020) Detailed reference viewed: 40 (6 UL) Opinion Statement ECJ-TF 2/2020 on the ECJ Decision of 3 March 2020 in Vodafone Magyarország Mobil Távközlési Zrt. (Case C-75/18) on Progressive Turnover Taxes; Haslehner, Werner ; et alin European Taxation (2020), 60(12), 555-564 This CFE Opinion Statement discusses the decision of the Grand Chamber of the ECJ in Vodafone. The Court held that the imposition of the Hungarian progressive turnover-based tax on the telecommunications ... [more ▼] This CFE Opinion Statement discusses the decision of the Grand Chamber of the ECJ in Vodafone. The Court held that the imposition of the Hungarian progressive turnover-based tax on the telecommunications sector did not infringe the EU fundamental freedoms or article 401 of the VAT Directive (2006/112), and that the question regarding the prohibition of State aid was inadmissible. Vodafone is especially important in respect of the current debate regarding turnover-based digital services taxes. [less ▲] Detailed reference viewed: 63 (1 UL) LogiKEy Workbench: Deontic Logics, Logic Combinations and Expressive Ethical and Legal Reasoning (Isabelle/HOL Dataset)Benzmüller, Christoph ; Farjami, Ali ; et alin Data in Brief (2020), 33 The LogiKEy workbench and dataset for ethical and legal reasoning is presented. This workbench simultaneously supports development, experimentation, assessment and deployment of formal logics and ethical ... [more ▼] The LogiKEy workbench and dataset for ethical and legal reasoning is presented. This workbench simultaneously supports development, experimentation, assessment and deployment of formal logics and ethical and legal theories at different conceptual layers. More concretely, it comprises, in form of a dataset (Isabelle/HOL theory files), formal encodings of multiple deontic logics, logic combinations, deontic paradoxes and normative theories in the higher-order proof assistant system Isabelle/HOL. The data were acquired through application of the LogiKEy methodology, which supports experimentation with different normative theories, in different application scenarios, and which is not tied to specific logics or logic combinations. Our workbench consolidates related research contributions of the authors and it may serve as a starting point for further studies and experiments in flexible and expressive ethical and legal reasoning. It may also support hands-on teaching of non-trivial logic formalisms in lecture courses and tutorials. [less ▲] Detailed reference viewed: 109 (5 UL) NOMA-Enabled Multi-Beam Satellite Systems: Joint Optimization to Overcome Offered-Requested Data MismatchesWang, Anyue ; Lei, Lei ; Lagunas, Eva et alin IEEE Transactions on Vehicular Technology (2020) Detailed reference viewed: 218 (35 UL) Lecture notes on Algebraic GeometryKalugin, Alexey ![]() Learning material (2020) Lecture notes for the course given by the author at the University of Luxembourg during the winter term 2020. Detailed reference viewed: 43 (3 UL) Simultaneous Diagonalization of Incomplete Matrices and ApplicationsCoron, Jean-Sébastien ; Notarnicola, Luca ; Wiese, Gabor ![]() in Proceedings of the Fourteenth Algorithmic Number Theory Symposium (ANTS-XIV), edited by Steven Galbraith, Open Book Series 4, Mathematical Sciences Publishers, Berkeley, 2020 (2020, December) We consider the problem of recovering the entries of diagonal matrices {U_a}_a for a = 1, . . . , t from multiple “incomplete” samples {W_a}_a of the form W_a = P U_a Q, where P and Q are unknown matrices ... [more ▼] We consider the problem of recovering the entries of diagonal matrices {U_a}_a for a = 1, . . . , t from multiple “incomplete” samples {W_a}_a of the form W_a = P U_a Q, where P and Q are unknown matrices of low rank. We devise practical algorithms for this problem depending on the ranks of P and Q. This problem finds its motivation in cryptanalysis: we show how to significantly improve previous algorithms for solving the approximate common divisor problem and breaking CLT13 cryptographic multilinear maps. [less ▲] Detailed reference viewed: 151 (23 UL) Un inventaire du patrimoine après une épidémie de démolitions?Pauly, Michel ![]() Article for general public (2020) plaidoyer pour l'introduction d'une procédure d'urgence dans le projet de loi 7473 afin d'éviter des démolitions en masse avant la finalisation de l'inventaire des monuments historiques Detailed reference viewed: 58 (3 UL) Self-Regulation of Fundamental Rights? The EU Code of Conduct on Hate Speech, Related Initiatives and BeyondQuintel, Teresa Alegra ; Ullrich, Carsten ![]() in Ojanen, Tuomas; Petkova, Bilyana (Eds.) Fundamental Rights Protection Online: the Future Regulation of Intermediaries (2020) This contribution will give a brief overview of EU legislation encouraging self-regulation, such as codes of conduct, communications and recommendations and propose an alternative approach towards ... [more ▼] This contribution will give a brief overview of EU legislation encouraging self-regulation, such as codes of conduct, communications and recommendations and propose an alternative approach towards fighting illegal content on online platforms, which ventures squarely into co-regulation. There is no formal and straightforward definition on what constitutes illegal hate speech. However, hate speech might be classified as targeting minority groups in a way that promotes violence or social disorder and hatred. The use of social media and online platforms to spread illegal content and hate speech has increased progressively during recent years, as content may be disseminated anonymously and further shared by other users. Therefore, the timely removal or blocking of access to illegal content is essential to limit the wider dissemination and harm of individuals targeted by hate speech. The prominent role of online platforms in revolutionizing modern communication and as influencers of the public opinion has increasingly come to the attention of policy makers. Since online platforms provide an important stage for phenomena such as ‘fake news’, ‘hate speech’ or ‘disinformation’, the pressure to take more responsibility over content hosted by them has grown. The EU Commission took action via several attempts to set certain rules for online intermediaries, mostly relying on non-binding agreements, often in the form of self-regulatory measures, such as codes of conduct, guidelines and recommendations. These measures have raised concerns regarding possible limitations of Freedom of Expression, because they require online platforms to adjudicate on the legality of content, often by relying on automated systems. Meanwhile decisions over the unlawfulness of hate speech and “disinformation” are often notoriously difficult. The deployment of algorithms to analyse the content generated on platforms, such as recognition and filtering technologies, bear risks and pitfalls of automated compliance solutions. Although the use of algorithms to monitor content online still happens based on the “human-in-the-loop principle”, the diligence and efficiency with which illegal content can be reviewed is also dependent on the financial capacity and resources of each company. In addition, these privatized removal procedures maybe influenced by commercial interests and lack effective appeals mechanisms. All these issues throw up serious questions about the democratic legitimacy of self-regulatory removal procedures An alternative solution, proposed in this article, would require platforms to apply a risk-based approach to preventing and removing illegal content. The norms and standards of such an approach would be based on duty of care and be subject to regulatory oversight. It is suggested that the current self-regulatory proposals be replaced by co-regulatory solutions. [less ▲] Detailed reference viewed: 280 (15 UL) Multiple Vulnerabilities: The Effects of Neighborhood Structural Changes upon Older Residents’ Mental Health and Perceptions of the Broader CommunitySettels, Jason ![]() in Journal of Community Psychology (2020) Neighborhoods' structural conditions are consequential for their social circumstances and residents' well‐being. Neighborhood effects might be accentuated among older residents because their daily ... [more ▼] Neighborhoods' structural conditions are consequential for their social circumstances and residents' well‐being. Neighborhood effects might be accentuated among older residents because their daily activities and social lives are more confined to their immediate communities. This study examines how changing neighborhood socioeconomic disadvantage affects older residents' depression and stress, as well as perceptions of neighborhood context. This study employed waves 2 (2010–2011) and 3 (2015–2016) of the National Social Life, Health, and Aging Project survey (N= 2357) and fixed‐effects linear regression models to study these relationships. While rising neighborhood socioeconomic disadvantage was associated with more depression and stress, it was negatively associated with overall neighborhood social capital and neighborhood social cohesion, and was only associated with lower perceptions of neighborhood safety among respondents who relocated to new neighborhoods. Beyond cross‐sectional associations, changing neighborhood socioeconomic disadvantage is associated with changes in mental health and perceptions of neighborhood social context. [less ▲] Detailed reference viewed: 38 (8 UL) Publicly provided healthcare and migrationMahe, Clotilde ![]() in Economics and Human Biology (2020), 39 Publicly provided healthcare has received growing attention. Debates have been fuelled by evidence on improved health and reduced poverty, and concerns over adverse labour market effects; concerns that ... [more ▼] Publicly provided healthcare has received growing attention. Debates have been fuelled by evidence on improved health and reduced poverty, and concerns over adverse labour market effects; concerns that are, to date, only supported by mixed empirical findings. This article examines whether publicly provided healthcare influences the decision to migrate. The spatial and temporal variation in the expansion of a non-contributory health insurance programme in Mexico, combined with the panel dimension and the timing of household survey data allows causal identification of the effect of increased coverage on migration. Difference-in-differences estimates reveal that accessing healthcare for free raises internal migration. The effect on international migration, costlier by nature, is statistically insignificant. Potential mechanisms include better health, the alleviation of financial constraints and a greater propensity to work. Results point to the relevance of including household members who have migrated in assessing the impacts of social health policies. They suggest that publicly provided healthcare could have multiplier effects on economic development and welfare by enabling labour force detachment of working-age members in affiliated households. [less ▲] Detailed reference viewed: 51 (5 UL) Lëtzebuerger Literatur a Schoul a Gesellschaft : literaturdidaktesch Erausfuerderungen a MéiglechkeetenThiltges, Sébastian ![]() in Fundstücke/Trouvailles (2018/2019) (2020) Detailed reference viewed: 26 (4 UL) Phase transition for the volume of high-dimensional random polytopes; ; Turchi, Nicola ![]() in Random Structures and Algorithms (2020) Detailed reference viewed: 77 (21 UL) Wireless Edge Caching: Modeling, Analysis, and OptimizationVu, Thang Xuan ; ; Chatzinotas, Symeon et alBook published by Cambridge University Press (2020) Understand both uncoded and coded caching techniques in future wireless network design. Expert authors present new techniques that will help you to improve backhaul, load minimization, deployment cost ... [more ▼] Understand both uncoded and coded caching techniques in future wireless network design. Expert authors present new techniques that will help you to improve backhaul, load minimization, deployment cost reduction, security, energy efficiency and the quality of the user experience. Covering topics from high-level architectures to specific requirement-oriented caching design and analysis, including big-data enabled caching, caching in cloud-assisted 5G networks, and security, this is an essential resource for academic researchers, postgraduate students and engineers working in wireless communications. [less ▲] Detailed reference viewed: 60 (11 UL) Écologie, culture, Grande Région : remarques introductives sur une relation plurielle et complexeThiltges, Sébastian ; in Thiltges, Sébastian; Solte-Gresser, Christiane (Eds.) Écologie culturelle et cultures écologiques dans la Grande Région (2020, December) Detailed reference viewed: 26 (0 UL) Changes in school alienation profiles among secondary school students and the role of teaching style: Results from a longitudinal study in Luxembourg and SwitzerlandHadjar, Andreas ; ; et alin International Journal of Educational Research (2020), early online What students think about school has a major impact on learning and academic achievement. The multi-domain concept of school alienation distinguishes between alienation from learning, from teachers and ... [more ▼] What students think about school has a major impact on learning and academic achievement. The multi-domain concept of school alienation distinguishes between alienation from learning, from teachers and from classmates. We aim to study a) alienation patterns among secondary school students, b) how school alienation profiles change from year 7 to year 9 and how secondary school students transition between profiles, and c) the role of teaching style for transitions between school alienation profiles. We draw on panel data of secondary school students from Luxembourg and Switzerland. Results of latent profile/latent transition analyses reveal distinct school alienation profiles, country differences and support for the idea that student-oriented, supportive teaching styles might prevent students from transitioning towards more-highly alienated profiles. [less ▲] Detailed reference viewed: 116 (3 UL) Age, Intentions and the Implicit Role of Out-Selection Factors of International MigrationBeine, Michel ![]() E-print/Working paper (2020) In this paper, I propose to isolate the role of age as a self-selection factor of international migration. The role of age is estimated on intended emigration rather than on observed outcomes of migration ... [more ▼] In this paper, I propose to isolate the role of age as a self-selection factor of international migration. The role of age is estimated on intended emigration rather than on observed outcomes of migration, using individual measures of intended emigration drawn from a large-scale survey conducted by Gallup. I find evidence that age has a monotonic negative effect on desired emigration for the working-age population. The estimations point to a very robust effect, suggesting that an additional year of age decreases the probability of intended emigration by about 0.5%. This effect is steady over different periods of time and for most types of countries of origin. The results contrast with previous evidence obtained on observed outcomes of migration, suggesting that out-selection factors interact with age and shape the demographic profile of migrants. [less ▲] Detailed reference viewed: 29 (4 UL) A hybrid MGA-MSGD ANN training approach for approximate solution of linear elliptic PDEsDehghani, Hamidreza ; Zilian, Andreas ![]() E-print/Working paper (2020) We introduce a hybrid "Modified Genetic Algorithm-Multilevel Stochastic Gradient Descent" (MGA-MSGD) training algorithm that considerably improves accuracy and efficiency of solving 3D mechanical problems ... [more ▼] We introduce a hybrid "Modified Genetic Algorithm-Multilevel Stochastic Gradient Descent" (MGA-MSGD) training algorithm that considerably improves accuracy and efficiency of solving 3D mechanical problems described, in strong-form, by PDEs via ANNs (Artificial Neural Networks). This presented approach allows the selection of a number of locations of interest at which the state variables are expected to fulfil the governing equations associated with a physical problem. Unlike classical PDE approximation methods such as finite differences or the finite element method, there is no need to establish and reconstruct the physical field quantity throughout the computational domain in order to predict the mechanical response at specific locations of interest. The basic idea of MGA-MSGD is the manipulation of the learnable parameters’ components responsible for the error explosion so that we can train the network with relatively larger learning rates which avoids trapping in local minima. The proposed training approach is less sensitive to the learning rate value, training points density and distribution, and the random initial parameters. The distance function to minimise is where we introduce the PDEs including any physical laws and conditions (so-called, Physics Informed ANN). The Genetic algorithm is modified to be suitable for this type of ANN in which a Coarse-level Stochastic Gradient Descent (CSGD) is exploited to make the decision of the offspring qualification. Employing the presented approach, a considerable improvement in both accuracy and efficiency, compared with standard training algorithms such classical SGD and Adam optimiser, is observed. The local displacement accuracy is studied and ensured by introducing the results of Finite Element Method (FEM) at sufficiently fine mesh as the reference displacements. A slightly more complex problem is solved ensuring the feasibility of the methodology [less ▲] Detailed reference viewed: 66 (1 UL) Perception of immigration to Iceland: The host country perspectiveMurdock, Elke ![]() in Meckl, Markus; Gunnþórsdóttir, Hermina (Eds.) Samfélag fjölbreytileikans: Samskipti heimamanna og innflytjenda á Íslandi. (2020) With 35.5 immigrants per 1000 inhabitants, Iceland had the third highest number of immigrants per inhabitants in Europe in 2018. Until the turn of the century, the foreign population percentage in Iceland ... [more ▼] With 35.5 immigrants per 1000 inhabitants, Iceland had the third highest number of immigrants per inhabitants in Europe in 2018. Until the turn of the century, the foreign population percentage in Iceland was around 2%. In the last 5 years, this percentage has risen steadily to nearly 14% in 2020. How is this rapid rise in immigration experienced by the host country population? How are immigrants perceived and what are expectations in terms of behavior? The Inclusive Societies – Iceland project investigated both, the immigrants’ situation in Iceland, but also the native populations’ attitude towards immigration and immigrants. It is important to take the host country perspective into consideration, as diversity ideologies will also determine the acculturation options for minorities. A quantitative survey was conducted among 3630 native Icelanders (51.1% women, MAge = 50.8, SD = 15.6), spread across all regions of Iceland. The questions covered a range of domains pertinent to life in Iceland. In this Chapter only the questions pertaining directly to immigration and immigrants are analyzed. The results indicate that culture contact takes place – with, over two thirds of participants indicating that they have invited immigrants to their home and slightly under two thirds having been invited to immigrants’ homes. Overall, the perception is that immigrants have made a positive impact to communities. The vast majority of participants expect immigrants to learn Icelandic. The greatest divergence of views was found concerning the question, if immigrants should adopt Icelandic customs and values. The findings will be discussed in light of policy implications. [less ▲] Detailed reference viewed: 86 (1 UL) |
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