Luxemburgische Musiker und luxemburgische Chormusik

Scientific Conference (1989, May)

GaInAs Camel Transistors Grown by MOCVD

in Electronics Letters (1989), 25(1989), 1462-1463

Einführung in die Wirtschaftspolitik. Theoretische Grundlagen und Anwendungsbeispiele

Book published by Vahlen, Franz (1989)

Der Dollar als internationale Schlüsselwährung: Ursachen und Perspektiven

in Kredit und Kapital (1989)

Action of atrial natriuretic peptide and angiotensin II on the myocardium: studies in isolated rat ventricular cardiomyocytes.

in Biochemical and biophysical research communications (1989), 163(3), 1435-43

Isolated calcium-tolerant rat ventricular cardiomyocytes were used to characterize the effects of atrial natriuretic peptide (ANP), Angiotensin II (AII) and their interaction on the myocardial contraction ... [more ▼]

Isolated calcium-tolerant rat ventricular cardiomyocytes were used to characterize the effects of atrial natriuretic peptide (ANP), Angiotensin II (AII) and their interaction on the myocardial contraction-/relaxation pattern free of interference from other types of cardiac cells. Binding of 125I-ANP showed a KD of 12 pM and approximately 600 binding sites per cell. At 37 degrees C (rate 140 bpm) ANP decreased the contraction maximum with an EC50 of about 70 pM, maximal decrease was 35%. ANP (10(-7) M) raised cellular cyclic-GMP from 0.76+/-0.12 to 1.32+/-0.13 pmole/10(6) cells (73%, p less than 0.05). Angiotensin II increased contractility by a maximum of 32% at 10(-7) M; the EC50 was 8 x 10(-10) M. AII markedly delayed relaxation (reduction of maximum relaxation velocity from 0.092 to 0.063 mm/s; p less than 0.05). ANP (10(-7) M) increased the effect of AII (10(-8) M) on contractility by 66% without changing relaxation parameters significantly. This unexpected interaction may be relevant in pathological conditions where both AII and ANP are stimulated, such as heart failure or secondary hypertension. [less ▲]

The detection and perveived intensity of noxious thermal stimuli in monkey and human

in Journal of Neurophysiology (1989), 62(2), 429-436

Art et révolution industrielle au pays de la terre rouge. Réflexions sur quelques oeuvres d'art de la collection de la ville d'Esch-sur-Alzette

in Scuto, Denis (Ed.) Esch-sur-Alzette, du village à la ville industrielle. Art et révolution industrielle au pays de la terre rouge (Catalogue d'exposition) (1989)

[Increased atrial natriuretic peptide in essential hypertension--relation to right atrial pressure behavior].

in Klinische Wochenschrift (1989), 67(15), 756-61

The role of atrial natriuretic peptide (ANP) in the pathogenesis of essential hypertension has not yet entirely been clarified. We investigated whether the increase of ANP in essential hypertension may be ... [more ▼]

The role of atrial natriuretic peptide (ANP) in the pathogenesis of essential hypertension has not yet entirely been clarified. We investigated whether the increase of ANP in essential hypertension may be explained by elevated right atrial pressures and/or a different relationship between right atrial pressures and ANP secretion. Patients with stable essential hypertension undergoing right and left heart catheterization because of suspected coronary heart disease had significantly higher ANP levels than normotensives: 58.7 +/- 6.7 pg/ml in hypertensives versus 42.0 +/- 4.1 pg/ml in normotensives (p less than 0.01). Matching hypertensives with normotensives at identical levels of left ventricular enddiastolic pressure revealed significantly higher mean pulmonary artery pressures in hypertensives. Right atrial diastolic pressure (v-wave) after matching for LVEDP was 4.8 +/- 0.5 mm Hg in hypertensives and 3.1 +/- 0.2 mm Hg in normotensives (p less than 0.05). In addition, at any given mean right atrial pressure hypertensives showed higher ANP levels than normotensives. These results demonstrate that hypertensives exhibit raised pressures in the pulmonary artery independent of left ventricular pressure load. The elevation in right atrial pressures and the steeper relationship between these pressures and ANP are a suitable explanation for raised ANP levels in hypertension. ANP in essential hypertension may represent a counterregulation against elevated pulmonary resistance. [less ▲]

Distribution of substance P and calcitonin gene-related peptide in articular afferent neurons

in Supplement ... to the European Journal of Neuroscience (1989), (Suppl. 2), 69

Industrialisation et urbanisation. L'exemple d'Esch-sur-Alzette

in Scuto, Denis (Ed.) Esch-sur-Alzette, du village à la ville industrielle. Art et révolution industrielle au pays de la terre rouge (Catalogue d'exposition) (1989)