References of "Walter, Jonas"
     in
Bookmark and Share    
Full Text
Peer Reviewed
See detailGeneration of two induced pluripotent stem cell lines and the corresponding isogenic controls from Parkinson’s disease patients carrying the heterozygous mutations c.815G>A (p.R272Q) or c.1348C>T (p.R450C) in the RHOT1 gene encoding Miro1
Chemla, Axel UL; Arena, Giuseppe UL; Onal, Gizem et al

in Stem Cell Research (2023)

Fibroblasts from two Parkinson’s disease (PD) patients carrying either the heterozygous mutation c.815G>A (Miro1 p.R272Q) or c.1348C>T (Miro1 p.R450C) in the RHOT1 gene, were converted into induced ... [more ▼]

Fibroblasts from two Parkinson’s disease (PD) patients carrying either the heterozygous mutation c.815G>A (Miro1 p.R272Q) or c.1348C>T (Miro1 p.R450C) in the RHOT1 gene, were converted into induced pluripotent stem cells (iPSCs) using RNA-based and episomal reprogramming, respectively. The corresponding isogenic gene-corrected lines have been generated using CRISPR/Cas9 technology. These two isogenic pairs will be used to study Miro1-related molecular mechanisms underlying neurodegeneration in relevant iPSC-derived neuronal models (e.g., midbrain dopaminergic neurons and astrocytes). [less ▲]

Detailed reference viewed: 207 (3 UL)
Full Text
Peer Reviewed
See detailThe Parkinson’s-disease-associated mutation LRRK2-G2019S alters dopaminergic differentiation dynamics via NR2F1
Walter, Jonas; Bolognin, Silvia UL; Poovathingal, Suresh et al

in Cell Reports (2021)

Detailed reference viewed: 180 (11 UL)
Full Text
Peer Reviewed
See detailParkinson’s disease phenotypes in patient neuronal cultures and brain organoids improved by 2-Hydroxypropyl-b-Cyclodextrin treatment
Jarazo, Javier UL; Barmpa, Kyriaki UL; Modamio, Jennifer et al

in Movement Disorders (2021)

Detailed reference viewed: 224 (25 UL)
Full Text
Peer Reviewed
See detailImpaired Mitochondrial-Endoplasmic Reticulum Interaction and Mitophagy in Miro1-Mutant Neurons in Parkinson’s Disease
Berenguer-Escuder, Clara; Grossmann, Dajana; Antony, Paul UL et al

in Human Molecular Genetics (2020)

Detailed reference viewed: 457 (27 UL)
Full Text
Peer Reviewed
See detailImpaired serine metabolism complements LRRK2-G2019S pathogenicity in PD patients
Nickels, Sarah UL; Walter, Jonas; Bolognin, Silvia UL et al

in Parkinsonism and Related Disorders (2019)

Detailed reference viewed: 333 (43 UL)
Full Text
Peer Reviewed
See detailNeural Stem Cells of Parkinson's Disease Patients Exhibit Aberrant Mitochondrial Morphology and Functionality
Walter, Jonas; Bolognin, Silvia UL; Antony, Paul UL et al

in Stem Cell Reports (2019)

Detailed reference viewed: 392 (37 UL)