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See detailFrom Network Analysis to Functional Metabolic Modeling of the Human Gut Microbiota
Bauer, Eugen; Thiele, Ines UL

in mSystems (2018)

An important hallmark of the human gut microbiota is its species diversity and complexity. Various diseases have been associated with a decreased diversity leading to reduced metabolic functionalities ... [more ▼]

An important hallmark of the human gut microbiota is its species diversity and complexity. Various diseases have been associated with a decreased diversity leading to reduced metabolic functionalities. Common approaches to investigate the human microbiota include high-throughput sequencing with subsequent correlative analyses. However, to understand the ecology of the human gut microbiota and consequently design novel treatments for diseases, it is important to represent the different interactions between microbes with their associated metabolites. Computational systems biology approaches can give further mechanistic insights by constructing data- or knowledge-driven networks that represent microbe interactions. In this minireview, we will discuss current approaches in systems biology to analyze the human gut microbiota, with a particular focus on constraint-based modeling. We will discuss various community modeling techniques with their advantages and differences, as well as their application to predict the metabolic mechanisms of intestinal microbial communities. Finally, we will discuss future perspectives and current challenges of simulating realistic and comprehensive models of the human gut microbiota. [less ▲]

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See detailArithmetic billiards
Perucca, Antonella UL

Article for general public (2018)

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See detailKorpusbasierte Untersuchung der Wortbildungsaffixe im Luxemburgischen. Technische Herausforderungen und linguistische Analyse am Beispiel der Produktivität
Sirajzade, Joshgun UL

in Zeitschrift für Wortbildung = Journal of Word Formation (2018), 2(1),

This article is a report about compiling a corpus of Luxembourgish for investigation of word formation. First it gives an example for benefits of using a corpus with annotations in investigation of ... [more ▼]

This article is a report about compiling a corpus of Luxembourgish for investigation of word formation. First it gives an example for benefits of using a corpus with annotations in investigation of productivity of some selected word formation affixes of Luxembourgish. Then it describes how this can be achieved from a technical point of view. [less ▲]

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See detailRegional Parliaments: Effective Actors in EU Policy-Making?
Abels, Gabriele; Högenauer, Anna-Lena UL

Book published by Routledge (2018)

In an attempt to strengthen the legitimacy of EU policy-making, the 2009 Lisbon Treaty strengthened the principle of parliamentary control in EU affairs. This pertains to parliaments at all levels ranging ... [more ▼]

In an attempt to strengthen the legitimacy of EU policy-making, the 2009 Lisbon Treaty strengthened the principle of parliamentary control in EU affairs. This pertains to parliaments at all levels ranging from the regional to the supranational level. This book analyses the potential of regional parliaments – the parliaments closest to the citizens – to engage in EU affairs and to fill the perceived legitimacy gap. Eight member states have a total of 73 regional parliaments with legislative powers, and there are further trends towards decentralization in Europe. On its quest to understand the role that regional parliaments can plan in the EU multilevel parliamentary system, the book addresses key questions: What are the formal powers and functions of regional parliaments in EU policy-making? How do they use their powers in practice? How active are they in EU politics and what do they try to achieve? What factors can explain their degree of (in-)activity? [less ▲]

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See detailModeling metabolism of the human gut microbiome
Magnusdottir, Stefania UL; Thiele, Ines UL

in Current Opinion in Biotechnology (2018)

The human gut microbiome plays an important part in human health. The complexity of the microbiome makes it difficult to determine the detailed metabolic functions and cross-talk occurs between the ... [more ▼]

The human gut microbiome plays an important part in human health. The complexity of the microbiome makes it difficult to determine the detailed metabolic functions and cross-talk occurs between the individual species. In silico systems biology studies of the microbiome can help to identify metabolite exchanges among gut microbes. Constraint-based reconstruction and analysis methods use biochemically accurate genome-scale metabolic networks of microorganisms to simulate metabolism between species in a given microbiome and help generate novel hypotheses on microbial interactions. Here, we review metabolic modeling studies that have investigated metabolic functions of the gut microbiome. [less ▲]

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See detailLocal curvature estimates for the Laplacian flow
Li, Yi UL

E-print/Working paper (2018)

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See detailLandesplanung noch nicht im Griff
Hesse, Markus UL

Article for general public (2018)

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See detailDetecting Malicious Authentication Events Trustfully
Kaiafas, Georgios UL; Varisteas, Georgios UL; Lagraa, Sofiane UL et al

in Kaiafas, Georgios; Varisteas, Georgios; Lagraa, Sofiane (Eds.) et al IEEE/IFIP Network Operations and Management Symposium, 23-27 April 2018, Taipei, Taiwan Cognitive Management in a Cyber World (2018)

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See detailIntegrated Protection of Industrial Control Systems from Cyber-attacks: the ATENA Approach
Adamsky, Florian UL; Aubigny, Matthieu; Battisti, Federica et al

in Elsevier International Journal of Critical Infrastructure Protection (2018)

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See detailMachine Learning for Reliable Network Attack Detection in SCADA Systems
Lopez Perez, Rocio; Adamsky, Florian UL; Soua, Ridha UL et al

in 17th IEEE International Conference On Trust, Security And Privacy In Computing And Communications (IEEE TrustCom-18) (2018)

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See detailSignaling-Dependent Control of Apical Membrane Size and Self-Renewal in Rosette-Stage Human Neuroepithelial Stem Cells
Medelnik, Jan-Philip; Roensch, Kathleen; Okawa, Satoshi UL et al

in Stem Cell Reports (2018)

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See detailLa désinstutionnalisation psychiatrique. Un phénomène introuvable en Belgique dans les années 1960 et 1970?
Majerus, Benoît UL

in Guillemain, Hervé; Klein, Alexandre; Thifault, Marie-Claude (Eds.) Fin de l’asile ?: histoire de la déshospitalisation psychiatrique dans l’espace francophone au XXe siècle (2018)

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See detailProva scientifica e dimensione europea
Allegrezza, Silvia UL

in Canzio, Giovanni; Luparia, Luca (Eds.) Prova scientifica e processo penale (2018)

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See detailDéterminants individuels et territoriaux des navettes internes ou transfrontalières des actifs résidant en France
Pigeron-Piroth, Isabelle UL; Le Texier, Marion; Belkacem, Rachid et al

in Espace, Populations, Sociétés (2018), 2017(3), 1-30

This article focuses on the individual and territorial determinants of cross-border commuting from France to its neighbouring countries. We seek to identify whether cross-border commuting is a distinct ... [more ▼]

This article focuses on the individual and territorial determinants of cross-border commuting from France to its neighbouring countries. We seek to identify whether cross-border commuting is a distinct form of commuting, especially whether it differs for an active resident from commuting outside his/her reference functional urban area. We use individual data from the 2013 census and characterize the territory at the municipal scale in order to capture the relative polarisation of residential places within the national urban system. From our multinomial logistic models applied to the whole France or the border fringe, we find that gender, age, education, type and sector of activity, as well as the location of the commune with respect to employment poles in France, explain similarly the commute of active individuals towards another urban area in France and across the border. However, the effect is more intensive for cross-border commuting. After controlling the impact of the different neighbouring countries, we still clearly identify a different behaviour from elastic migrants in border areas and an effect of the distance to the border and of the job density on the cross-border commutes. [less ▲]

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See detailLe terrorisme esthétique comme antidote
Roelens, Nathalie UL

in Raison publique (2018)

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See detailFailure behaviour of silicone adhesive in bonded connections with simple geometry
Staudt, Yves UL; Odenbreit, Christoph UL; Schneider, Jens

in International Journal of Adhesion & Adhesives (2018), 82

In façade structures, adhesively bonded connections between glass panels and metallic substructures represent an attractive alternative to mechanical fixation devices. Apart from positive aspects ... [more ▼]

In façade structures, adhesively bonded connections between glass panels and metallic substructures represent an attractive alternative to mechanical fixation devices. Apart from positive aspects regarding the construction's energy efficiency and aesthetics, the uniform load transfer reduces stress concentrations in the adherends, which is beneficial especially regarding brittle materials like glass. Structural silicone sealants are generally used for these kind of applications due to their excellent adhesion on glass and their exceptional resistance against environmental influences and ageing. For the verification of the bonded connection, non-linear numerical simulations, such as the Finite Element Method, are increasingly used. The resulting three-dimensional stress states need to be assessed with the help of an appropriate failure criterion. In this paper, an overview is given on available failure criteria for rubber-like materials. The applicability of these criteria on the silicone sealant is verified regarding three characteristic stress states: uniaxial tension, shear and compression. The proposed engineering failure criterion is the true strain magnitude, which is valid for bonded connections in form of linear beads for cohesive failure of the adhesive. For Dow Corning® 993 structural silicone sealant, the strain magnitude, evaluated using true strains, at failure could be determined as 1.6. [less ▲]

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See detailHidden Beneath the Surface: Origin of the Observed Enantioselective Adsorption on PdGa(111)
Yakutovich, Aliaksandr V.; Hoja, Johannes UL; Passerone, Daniele et al

in Journal of the American Chemical Society (2018), 140(4), 1401-1408

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See detailChaos-enhanced mobility models for multilevel swarms of UAVs
Rosalie, Martin UL; Danoy, Grégoire UL; Chaumette, Serge et al

in Swarm and Evolutionary Computation (2018)

The number of civilian and military applications using Unmanned Aerial Vehicles (UAVs) has increased during the last years and the forecasts for upcoming years are exponential. One of the current major ... [more ▼]

The number of civilian and military applications using Unmanned Aerial Vehicles (UAVs) has increased during the last years and the forecasts for upcoming years are exponential. One of the current major challenges consist in considering UAVs as autonomous swarms to address some limitations of single UAV usage such as autonomy, range of operation and resilience. In this article we propose novel mobility models for multi-level swarms of collaborating UAVs used for the coverage of a given area. These mobility models generate unpredictable trajectories using a chaotic solution of a dynamical system. We detail how the chaotic properties are used to structure the exploration of an unknown area and enhance the exploration part of an Ant Colony Optimization method. Empirical evidence of the improvement of the coverage efficiency obtained by our mobility models is provided via simulation. It clearly outperforms state-of-the-art approaches. [less ▲]

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See detailA Revisit of Action Detection using Improved Trajectories
Papadopoulos, Konstantinos UL; Antunes, Michel; Aouada, Djamila UL et al

in IEEE International Conference on Acoustics, Speech and Signal Processing, Calgary, Alberta, Canada, 15–20 April 2018 (2018)

In this paper, we revisit trajectory-based action detection in a potent and non-uniform way. Improved trajectories have been proven to be an effective model for motion description in action recognition ... [more ▼]

In this paper, we revisit trajectory-based action detection in a potent and non-uniform way. Improved trajectories have been proven to be an effective model for motion description in action recognition. In temporal action localization, however, this approach is not efficiently exploited. Trajectory features extracted from uniform video segments result in significant performance degradation due to two reasons: (a) during uniform segmentation, a significant amount of noise is often added to the main action and (b) partial actions can have negative impact in classifier's performance. Since uniform video segmentation seems to be insufficient for this task, we propose a two-step supervised non-uniform segmentation, performed in an online manner. Action proposals are generated using either 2D or 3D data, therefore action classification can be directly performed on them using the standard improved trajectories approach. We experimentally compare our method with other approaches and we show improved performance on a challenging online action detection dataset. [less ▲]

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