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See detailThe Effects of Deskilling and Unemployment on Hiring Decisions
Samuel, Robin UL; Imdorf, Christian; Sacchi, Stefan et al

Scientific Conference (2017, November 08)

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See detailUniversal health coverage: an urgent need for collaborative learning and technology in primary care
Patel, Kunal D.; Mcloughlin, Clodagh; Lygidakis, Charilaos UL et al

in Education for Primary Care (2017)

Universal health coverage is an achievable goal for all health professionals globally. However, for it to be implemented technology and collaboration are essential. This letter focuses on recently ... [more ▼]

Universal health coverage is an achievable goal for all health professionals globally. However, for it to be implemented technology and collaboration are essential. This letter focuses on recently published recommendations for technology in primary care education in respect to Universal Health Coverage. [less ▲]

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See detailPROFICIENT: Productivity Tool for Semantic Interoperability in an Open IoT Ecosystem
Kolbe, Niklas UL; Robert, Jérémy UL; Kubler, Sylvain et al

in Proceedings of the 14th EAI International Conference on Mobile and Ubiquitous Systems: Computing, Networking and Services (2017)

The Internet of Things (IoT) is promising to open up opportunities for businesses to offer new services to uncover untapped needs. However, before taking advantage of such opportunities, there are still ... [more ▼]

The Internet of Things (IoT) is promising to open up opportunities for businesses to offer new services to uncover untapped needs. However, before taking advantage of such opportunities, there are still challenges ahead, one of which is the development of strategies to abstract from the heterogeneity of APIs that shape today's IoT. It is becoming increasingly complex for developers and smart connected objects to efficiently discover, parse, aggregate and process data from disparate information systems, as different protocols, data models, and serializations for APIs exist on the market. Standards play an indisputable role in reducing such a complexity, but will not solve all problems related to interoperability. For example, it will remain a permanent need to help and guide data/service providers to efficiently describe the data/services they would like to expose to the IoT. This paper presents PROFICIENT, a productivity tool that fulfills this need, which is showcased and evaluated considering recent open messaging standards and a smart parking scenario. [less ▲]

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See detailRandomised controlled non-inferiority trial of primary care-based facilitated access to an alcohol reduction website
Wallace, Paul; Struzzo, Pierliugi; Della Vedova, Roberto et al

in BMJ Open (2017), 7(11),

Background: Brief interventions (BIs) delivered in primary care have been shown to be effective in reducing risky drinking, but implementation is limited. Facilitated access to a digital application ... [more ▼]

Background: Brief interventions (BIs) delivered in primary care have been shown to be effective in reducing risky drinking, but implementation is limited. Facilitated access to a digital application offers a novel alternative to face-to-face intervention, but its relative effectiveness is unknown.Methods: Primary care-based, non-inferiority, randomised controlled trial comparing general practitioner (GP) facilitated access to an interactive alcohol reduction website (FA) with face-to-face BI for risky drinking. Patients screening positive on the short Alcohol Use Disorders Identification Test (AUDIT-C) were invited to participate in the trial. Assessment at baseline, 3 months and 12 months was carried out using AUDIT and EQ-5D-5L questionnaires. Findings: 58 participating GPs approached 9080 patients of whom 4529 (49.9%) logged on, 3841 (84.8%) undertook screening, 822 (21.4%) screened positive and 763 (19.9%) were recruited. 347 (45.5%) were allocated to FA and 416 (54.5%) to BI. At 3 months, subjects in FA group with an AUDIT score of ≥8 reduced from 95 (27.5%) to 85 (26.8%) while those in BI group increased from 123 (20.6%) to 141 (37%). Differences between groups were principally due to responses to AUDIT question 10. Analysis of primary outcome indicated non-inferiority of FA compared with BI, and prespecified subgroup analysis indicated benefits for older patients and those with higher levels of computer literacy and lower baseline severity. Additional analyses undertaken to take account of bias in response to AUDIT question 10 failed to support non-inferiority within the prespecified 10% boundary.Interpretation: Prespecified protocol-driven analyses of the trial indicate that FA is non-inferior to BI; however, identified bias in the outcome measure and further supportive analyses question the robustness of this finding. It is therefore not possible to draw firm conclusions from this trial, and further research is needed to determine whether the findings can be replicated using more robust outcome measures.Trial registration number NCT01638338; Results. [less ▲]

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See detailInternetdelikte und die Herausforderungen des Forum Shoppings
Schmitz, Sandra UL

E-print/Working paper (2017)

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See detailMetaphors in Digital Hermeneutics: Zooming through Literary, Didactic and Historical Representations of Imaginary and Existing Cities
Armaselu, Florentina UL; van den Heuvel, Charles

in Digital Humanities Quarterly (2017), 11(3),

The paper proposes to bridge two areas of inquiry, digital hermeneutics and metaphor within a digital environment, by the analysis of a less studied phenomenon, i.e. how interpretation is supported and ... [more ▼]

The paper proposes to bridge two areas of inquiry, digital hermeneutics and metaphor within a digital environment, by the analysis of a less studied phenomenon, i.e. how interpretation is supported and shaped by metaphors embedded in an interface. The study is articulated around three use cases for literary, didactic and historical representations of imaginary and existing cities based on a model (z-text) and interface (Z-editor) for zoomable texts. We will try to demonstrate that the zooming and contextualization features of the tool allow creating layers of meaning that can assist interpretation and critical readings of literature and history. [less ▲]

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See detailKontaktraum für die einen, Filter für die anderen
Nienaber, Birte UL

Article for general public (2017)

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See detailOn the combined effect of periodic signals and colored noise on velocity uncertainties
Klos, Anna; Olivares Pulido, German UL; Teferle, Felix Norman UL et al

in GPS Solutions (2017)

The velocity estimates and their uncertainties derived from position time series of Global Navigation Satellite System stations are affected by seasonal signals and their harmonics, and the statistical ... [more ▼]

The velocity estimates and their uncertainties derived from position time series of Global Navigation Satellite System stations are affected by seasonal signals and their harmonics, and the statistical properties, i.e., the stochastic noise, contained in the series. If the deterministic model in the form of linear trend and periodic terms is not accurate enough to describe the time series, it will alter the stochastic model, and the resulting effect on the velocity uncertainties can be perceived as a result of a misfit of the deterministic model. The effects of insufficiently modeled seasonal signals will propagate into the stochastic model and falsify the results of the noise analysis, in addition to velocity estimates and their uncertainties. We provide the general dilution of precision (GDP) of velocity uncertainties as the ratio of uncertainties of velocities determined from to two different deterministic models while accounting for stochastic noise at the same time. In this newly defined GDP, the first deterministic model includes a linear trend, while the second one includes a linear trend and seasonal signals. These two are tested with the assumption of white noise only as well as the combinations of power-law and white noise in the data. The more seasonal terms are added to the series, the more biased the velocity uncertainties become. With increasing time span of observations, the assumption of seasonal signals becomes less important, and the power-law character of the residuals starts to play a crucial role in the determined velocity uncertainties. With reference frame and sea level applications in mind, we argue that 7 and 9 years of continuous observations is the threshold for white and flicker noise, respectively, while 17 years are required for random-walk to decrease GDP below 5% and to omit periodic oscillations in the GNSS-derived time series taking only the noise model into consideration. [less ▲]

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See detailBischof, Bürger und Hospital. Städtische Autonomie und bischöfliche Präsenz
Pauly, Michel UL

in Bihrer, Andreas; Fouquet, Gerhard (Eds.) Bischofsstadt ohne Bischof? Präsenz, Interaktion und Hoforganisation in bischöflichen Städten des Mittelalters (1300-1600) (2017)

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See detailIm Reich der spitzen Töne. Willy Mommer jun. (1921-1972): Musiker, Spion, Kulturmanager
Mommer, Marie-Claire; Brüll, Christoph UL

Book published by Grenz-Echo (2017)

Willy Mommer jun. (1921-1972), eminenter Vertreter der wohl bedeutendsten Eupener Musikerfamilie, erlangte als Dirigent, Komponist und Kulturmanager internationale Ausstrahlung. Doch hinter dem Künstler ... [more ▼]

Willy Mommer jun. (1921-1972), eminenter Vertreter der wohl bedeutendsten Eupener Musikerfamilie, erlangte als Dirigent, Komponist und Kulturmanager internationale Ausstrahlung. Doch hinter dem Künstler verbirgt sich auch eine der spannendsten Kriegsbiografien unserer Region. Als Funker beim deutschen militärischen Nachrichtendienst („Abwehr“) in Münster, Köln und Belzig bei Berlin konnte er sich durch seine pianistische Meisterschaft Zugang zum höchsten Machtzirkel des Militärs verschaffen und auf diese Weise den belgischen Widerstand und die britischen Nachrichtendienste mit kriegswichtigen Informationen versorgen. Marie-Claire Mommer und Christoph Brüll suchen in diesem Buch nach Spuren aus dem Leben Willy Mommers und verarbeiten sie zu einer literarischen und historischen Annäherung an eine Grenzen überschreitende Persönlichkeit und an einen leidenschaftlichen Europäer. [less ▲]

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See detailCompetition between crystal and fibril formation in molecular mutations of amyloidogenic peptides
Reynolds, Nicholas; Adamcik, Jozef; Berryman, Josh UL et al

in Nature Communications (2017), 8

Amyloidogenic model peptides are invaluable for investigating assembly mechanisms in disease related amyloids and in protein folding. During aggregation, such peptides can undergo bifurcation leading to ... [more ▼]

Amyloidogenic model peptides are invaluable for investigating assembly mechanisms in disease related amyloids and in protein folding. During aggregation, such peptides can undergo bifurcation leading to fibrils or crystals, however the mechanisms of fibril-to-crystal conversion are unclear. We navigate herein the energy landscape of amyloidogenic peptides by studying a homologous series of hexapeptides found in animal, human and disease related proteins. We observe fibril-to-crystal conversion occurring within single aggregates via untwisting of twisted ribbon fibrils possessing saddle-like curvature and cross-sectional aspect ratios approaching unity. Changing sequence, pH or concentration shifts the growth towards larger aspect ratio species assembling into stable helical ribbons possessing mean-curvature. By comparing atomistic calculations of desolvation energies for association of peptides we parameterise a kinetic model, providing a physical explanation of fibril-to-crystal interconversion. These results shed light on the self-assembly of amyloidogenic peptides, suggesting amyloid crystals, not fibrils, represent the ground state of the protein folding energy landscape. [less ▲]

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See detailRandomised controlled non-inferiority trial of primary care-based facilitated access to an alcohol reduction website: cost-effectiveness analysis
Hunter, Rachael; Wallace, Paul; Struzzo, Pierluigi et al

in BMJ Open (2017), 7(11),

Objectives To evaluate the 12-month costs and quality-adjusted life years (QALYs) gained to the Italian National Health Service of facilitated access to a website for hazardous drinkers compared with a ... [more ▼]

Objectives To evaluate the 12-month costs and quality-adjusted life years (QALYs) gained to the Italian National Health Service of facilitated access to a website for hazardous drinkers compared with a standard face-to-face brief intervention (BI). Design Randomised 1:1 non-inferiority trial. Setting Practices of 58 general practitioners (GPs) in Italy. Participants Of 9080 patients (>18 years old) approached to take part in the trial, 4529 (49·9%) logged on to the website and 3841 (84.8%) undertook online screening for hazardous drinking. 822 (21.4%) screened positive and 763 (19.9%) were recruited to the trial. Interventions Patients were randomised to receive either a face-to-face BI or access via a brochure from their GP to an alcohol reduction website (facilitated access). Primary and secondary outcome measures The primary outcome is the cost per QALY gained of facilitated access compared with face-to-face. A secondary analysis includes total costs and benefits per 100 patients, including number of hazardous drinkers prevented at 12 months. Results The average time required for the face-to-face BI was 8 min (95% CI 7.5 min to 8.6 min). Given the maximum time taken for facilitated access of 5 min, face-to-face is an additional 3 min: equivalent to having time for another GP appointment for every three patients referred to the website. Complete case analysis adjusting for baseline the difference in QALYs for facilitated access is 0.002 QALYs per patient (95% CI −0.007 to 0.011). Conclusions Facilitated access to a website to reduce hazardous drinking costs less than a face-to-face BI given by a GP with no worse outcomes. The lower cost of facilitated access, particularly in regards to investment of time, may facilitate the increase in provision of BIs for hazardous drinking. Trial registration number NCT01638338;Post-results. [less ▲]

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See detailÜbergewicht bei Schülern in Luxemburg
Residori, Caroline UL; Kern, Matthias Robert UL; Heinz, Andreas UL et al

E-print/Working paper (2017)

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See detailLuxembourg National Report: Tax Avoidance Revisited in the EU BEPS Context
Haslehner, Werner UL

in Dourado, Ana Paula (Ed.) Tax Avoidance Revisited in the EU BEPS Context (2017)

This contribution analyses the status quo of anti-tax avoidance laws and doctrines in Luxembourg in reflection of the developments from the OECD BEPS project and the EU's reaction thereto. Starting from ... [more ▼]

This contribution analyses the status quo of anti-tax avoidance laws and doctrines in Luxembourg in reflection of the developments from the OECD BEPS project and the EU's reaction thereto. Starting from the traditional approach taken by the Luxembourg courts to the term "Steuerumgehung" in §6 StAnpG, it also refers to special and target anti-avoidance rules (SAARs and TAARs) notably in the area of transfer pricing. Please note that the contribution was finalised in summer 2016 and the initial temporal scope of the study had been set until the end of 2015. Later developments, in particular changes to transfer pricing in Luxembourg (Art. 56bis LIR) could therefore not be taken into account. [less ▲]

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See detailBesteuerung der digitalen Wirtschaft in Großbritannien, Italien und Ungarn - ein europäischer Rechtsvergleich
Sinnig, Julia UL

in Internationale Steuer-Rundschau : Zeitschrift für Internationales Steuerrecht (2017), 6(11), 408-413

The "digital economy", a well-established notion in international tax law, is problematic for national legislatures and causes concern in the realm of international administrative assistance. At issue is ... [more ▼]

The "digital economy", a well-established notion in international tax law, is problematic for national legislatures and causes concern in the realm of international administrative assistance. At issue is the fundamental basis of the jurisdiction to tax: the genuine link between income generated by a digital business model and a specific territory, which is not easily identifiable under existing international tax concepts and far from digital economic reality. Multinational digital enterprises, however, are especially able to benefit from tax planning strategies that are even more favored by outdated international tax concepts. Negotiations and efforts to find international consensus on adaptations of existing tax concepts to intangible business models have been lengthy and so far unsuccessful. Consequently, recently some States have begun implementing unilateral measures to modernise digital economy taxation. This note presents the solutions of the United Kingdom, Italy and Hungary to adapt their income tax systems to the digital economy. [less ▲]

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See detailPartis politiques et religions en Europe 2016-2017
Poirier, Philippe UL

in Reynié, Dominique (Ed.) L'opinion européenne en 2017 (2017)

Pour la dix-huitième année, les auteurs de « L opinion européenne » traquent l émergence d une conscience et d une culture propre à tous ceux qui, de l Atlantique à l Oural, de Gibraltar à Trondheim, font ... [more ▼]

Pour la dix-huitième année, les auteurs de « L opinion européenne » traquent l émergence d une conscience et d une culture propre à tous ceux qui, de l Atlantique à l Oural, de Gibraltar à Trondheim, font l âme du Vieux Continent ! Un ouvrage de référence, attendu chaque année par tous les observateurs de l Europe en marche ! [less ▲]

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See detailPhonetik, Phonologie und Schrift
Dahmen, Silvia; Weth, Constanze UL

Book published by Ferdinand Schöningh (2017)

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See detailBausteng Grammatik - Bausteine Grammatik - Briques de Grammaire
Weth, Constanze UL

Book published by SCRIPT (2017)

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See detailOptimising Packet Forwarding in Multi-Tenant Networks using Rule Compilation
Hommes, Stefan UL; Valtchev, Petko; Blaiech, Khalil et al

in Optimising Packet Forwarding in Multi-Tenant Networks using Rule Compilation (2017, November)

Packet forwarding in Software-Defined Networks (SDN) relies on a centralised network controller which enforces network policies expressed as forwarding rules. Rules are deployed as sets of entries into ... [more ▼]

Packet forwarding in Software-Defined Networks (SDN) relies on a centralised network controller which enforces network policies expressed as forwarding rules. Rules are deployed as sets of entries into network device tables. With heterogeneous devices, deployment is strongly bounded by the respective table constraints (size, lookup time, etc.) and forwarding pipelines. Hence, minimising the overall number of entries is paramount in reducing resource consumption and speeding up the search. Moreover, since multiple control plane applications can deploy own rules, conflicts may occur. To avoid those and ensure overall correctness, a rule validation mechanism is required. Here, we present a compilation mechanism for rules of diverging origins that minimises the number of entries. Since it exploits the semantics of rules and entries, our compiler fits a heterogeneous landscape of network devices. We evaluated compiler implementations on both software and hardware switches using a realistic testbed. Experimental results show a reduction in both produced table entries and forwarding delay. [less ▲]

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See detailYour Moves, Your Device: Establishing Behavior Profiles Using Tensors
Falk, Eric UL; Charlier, Jérémy Henri J. UL; State, Radu UL

in Advanced Data Mining and Applications - 13th International Conference, ADMA 2017 (2017, November)

Smartphones became a person's constant companion. As the strictly personal devices they are, they gradually enable the replacement of well established activities as for instance payments, two factor ... [more ▼]

Smartphones became a person's constant companion. As the strictly personal devices they are, they gradually enable the replacement of well established activities as for instance payments, two factor authentication or personal assistants. In addition, Internet of Things (IoT) gadgets extend the capabilities of the latter even further. Devices such as body worn fitness trackers allow users to keep track of daily activities by periodically synchronizing data with the smartphone and ultimately with the vendor's computational centers in the cloud. These fitness trackers are equipped with an array of sensors to measure the movements of the device, to derive information as step counts or make assessments about sleep quality. We capture the raw sensor data from wrist-worn activity trackers to model a biometric behavior profile of the carrier. We establish and present techniques to determine rather the original person, who trained the model, is currently wearing the bracelet or another individual. Our contribution is based on CANDECOMP/PARAFAC (CP) tensor decomposition so that computational complexity facilitates: the execution on light computational devices on low precision settings, or the migration to stronger CPUs or to the cloud, for high to very high granularity. This precision parameter allows the security layer to be adaptable, in order to be compliant with the requirements set by the use cases. We show that our approach identifies users with high confidence. [less ▲]

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