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See detailThe Giant has woken up: the European Union’s Plans for the Future of Artificial Intelligence (AI)
Kafteranis, Dimitrios UL

in Irish Journal for European Law (2018), 21

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See detailTax and the Digital Economy – Bericht zur Konferenz vom 20.4.2018, Universität Luxemburg
Sinnig, Julia UL

in Internationale Steuer-Rundschau : Zeitschrift für Internationales Steuerrecht (2018), 7(6), 225-226

The ATOZ Chair for European and International Taxation of the University of Luxembourg invited renowned tax experts to discuss “Tax and the Digital Economy” on 20 April 2018; one month after the OECD ... [more ▼]

The ATOZ Chair for European and International Taxation of the University of Luxembourg invited renowned tax experts to discuss “Tax and the Digital Economy” on 20 April 2018; one month after the OECD published its 2018 interim report on BEPS Action 1 and the EU Commission its proposals on significant digital presence and a digital services tax. [less ▲]

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See detailTrends and transitions
Vögele, Claus UL

in European Journal of Health Psychology (2018), 25(1), 1

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See detailZeitschrift für interkulturelle Germanistik
Amann, Wilhelm UL; Dembeck, Till UL; Heimböckel, Dieter UL et al

in ZiG (2018), 9(2),

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See detailHybrid Ni/SiO2/Au dimer arrays for high-resolution refractive index sensing
Pourjamal, Sara; Kataja, Mikko; Maccaferri, Nicolo UL et al

in NANOPHOTONICS (2018), 7(5), 905-912

We introduce a novel magnetoplasmonic sensor concept for sensitive detection of refractive index changes. The sensor consists of a periodic array of Ni/SiO2/Au direr nanodisks. Combined effects of near ... [more ▼]

We introduce a novel magnetoplasmonic sensor concept for sensitive detection of refractive index changes. The sensor consists of a periodic array of Ni/SiO2/Au direr nanodisks. Combined effects of near-field interactions between the Ni and Au disks within the individual dimers and far-field diffractive coupling between the dimers of the array produce narrow linewidth features in the magneto-optical Faraday spectrum. We associate these features with the excitation of surface lattice resonances and show that they exhibit a spectral shift when the refractive index of the surrounding environment is varied. Because the resonances are sharp, refractive index changes are accurately detected by tracking the wavelength where the Faraday signal crosses 0. Compared to random distributions of pure Ni nanodisks or Ni/SiO2/Au dimers or periodic arrays of Ni nanodisks, the sensing figure of merit of the hybrid magnetoplasmonic array is more than one order of magnitude larger. [less ▲]

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See detailLive Intracellular Biorthogonal Imaging by Surface Enhanced Raman Spectroscopy using Alkyne-Silver Nanoparticles Clusters (vol 8, 15910, 2018)
Ardini, Matteo; Huang, Jian-An; Sanchez, Carlos S. et al

in SCIENTIFIC REPORTS (2018), 8

Live intracellular imaging is a valuable tool in modern diagnostics and pharmacology. Surface Enhanced Raman Spectroscopy (SERS) stands out as a non-destructive and multiplexed technique, but ... [more ▼]

Live intracellular imaging is a valuable tool in modern diagnostics and pharmacology. Surface Enhanced Raman Spectroscopy (SERS) stands out as a non-destructive and multiplexed technique, but intracellular SERS imaging still suffers from interfering background from endogenous components. Here we show the assembly of small colloidal SERS probes with Raman signal in the cell-silent window of 1800–2900 cm−1 for biorthogonal intracellular SERS imaging of dopamine that was undistinguishable from the endogenous cell background. By linking colloidal silver nanoparticles with alkyne-dopamine adducts, clusters are formed by 2–6 nanoparticles spaced by tight interparticle gaps that exhibited high electric field enhancement and strong SERS signals of alkyne and dopamines. Due to the cell-silent signals of the alkyne, intracellular in-vitro Raman imaging shows that the dopamines on the internalized clusters remain distinguishable across the cytoplasm with good spatial resolution. Our method can be a general-purpose method for real-time imaging of biomolecules, such as proteins, peptides, DNA and drugs. [less ▲]

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See detailZeitschrift für interkulturelle Germanistik
Heimböckel, Dieter UL; Mein, Georg UL; Schiewer, Gesine Lenore et al

in ZiG (2018), 9(1),

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See detailStill comparing apples with oranges? Some thoughts on the principles and practices of measurement invariance testing
Greiff, Samuel UL; Scherer, R.

in European Journal of Psychological Assessment (2018), 34

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See detailTagungsbericht: 71. International Fiscal Association Kongress 2017
Sinnig, Julia UL

in Internationale Steuer-Rundschau : Zeitschrift für Internationales Steuerrecht (2017), 6(12), 453-460

The 71st International Fiscal Association (IFA) Congress took place from 27 August to 1 September 2017 in Rio de Janeiro. The two main subjects of the congress were dedicated to the status quo of the base ... [more ▼]

The 71st International Fiscal Association (IFA) Congress took place from 27 August to 1 September 2017 in Rio de Janeiro. The two main subjects of the congress were dedicated to the status quo of the base erosion and profit shifting (BEPS) project and the future of transfer pricing. In addition, further seminars covered ten other topics. [less ▲]

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See detailA Hardware/Software Stack for Heterogeneous Systems
Castrillon, Jeronimo; Lieber, Matthias; Klueppelholz, Sascha et al

in IEEE Transactions on Multi-Scale Computing Systems (2017), PP(99), 1

Plenty of novel emerging technologies are being proposed and evaluated today, mostly at the device and circuit levels. It is unclear what the impact of different new technologies at the system level will ... [more ▼]

Plenty of novel emerging technologies are being proposed and evaluated today, mostly at the device and circuit levels. It is unclear what the impact of different new technologies at the system level will be. What is clear, however, is that new technologies will make their way into systems and will increase the already high complexity of heterogeneous parallel computing platforms, making it ever so difficult to program them. This paper discusses a programming stack for heterogeneous systems that combines and adapts well-understood principles from different areas, including capability-based operating systems, adaptive application runtimes, dataflow programming models, and model checking. We argue why we think that these principles built into the stack and the interfaces among the layers will also be applicable to future systems that integrate heterogeneous technologies. The programming stack is evaluated on a tiled heterogeneous multicore. [less ▲]

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See detailMagnetoplasmonic control of plasmonic vortices
Maccaferri, Nicolo UL; Gorodetski, Yuri; Toma, Andrea et al

in APPLIED PHYSICS LETTERS (2017), 111(20),

We theoretically investigate the generation of far-field propagating optical beams with a desired orbital angular momentum by using an archetypical magnetoplasmonic tip surrounded by a gold spiral slit ... [more ▼]

We theoretically investigate the generation of far-field propagating optical beams with a desired orbital angular momentum by using an archetypical magnetoplasmonic tip surrounded by a gold spiral slit. The use of a magnetic material can lead to important implications once magneto-optical activity is activated through the application of an external magnetic field. The physical model and the numerical study presented here introduce the concept of magnetically tunable plasmonic vortex lens, namely a magnetoplasmonic vortex lens, which ensures a tunable selectivity in the polarization state of the generated nanostructured beam. The presented system provides a promising platform for a localized excitation of plasmonic vortices followed by their beaming in the far-field with an active modulation of both light's transmission and helicity. Published by AIP Publishing. [less ▲]

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See detailZeitschrift für interkulturelle Germanistik
Heimböckel, Dieter UL; Mein, Georg UL; Schiewer, Gesine Lenore et al

in ZiG (2017), 8(1),

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See detailZeitschrift für interkulturelle Germanistik
Heimböckel, Dieter UL; Mein, Georg UL; Schiewer, Gesine Lenore et al

in ZiG (2017), 8(2),

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See detailTechnological addictions: Conceptualisation, measurement, etiology and treatment.
Kuss, Daria J.; Billieux, Joël UL

in Addictive behaviors (2017), 64

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See detailKommunikation im Fokus der Elementarpädagogik
Andersen, Katja Natalie UL

in KiTa aktuell HRS - Fachzeitschrift für Leitungen, Fachkräfte und Träger der Kindertagesbetreuung (2017), 25(5), 97

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See detailChronique Administration européenne Principes du droit administratif européen
Neframi, Eleftheria UL

in Revue Française d'Administration Publique (2017)

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See detailChronique Administration européenne Principes du droit administratif européen
Neframi, Eleftheria UL

in Revue Française d'Administration Publique (2016)

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See detailChronique Administration européenne Principes du droit administratif européen
Neframi, Eleftheria UL

in Revue Française d'Administration Publique (2016)

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See detailGroßschutzgebiete, Biodiversität und räumliche Planung. Ein Positionspapier aus der Akademie für Raumforschung und Landesplanung
Heiland, Stefan; Jedicke, Eckhardt; Job, Hubert et al

in Naturschutz und Landschaftsplanung (2016), 48(9),

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See detailZeitschrift für interkulturelle Germanistik
Heimböckel, Dieter UL; Mein, Georg UL; Schiewer, Lenore Gesine et al

in ZiG (2016), 7(2),

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See detailThe EU and The Human Right to Water and Sanitation: Normative Coherence as the Key to Transformative Development
Koff, Harlan UL; Maganda, Carmen

in EUROPEAN JOURNAL OF DEVELOPMENT RESEARCH (2016), 28(1), 91-110

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See detailGuest Editorial
Stadler, Matthias UL; Greiff, Samuel UL; Krolak-Schwerdt, Sabine UL

in Special Issue: Current Methodological Issues in Educational Large-Scale Assessments – Part I (2016), 58

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See detailZeitschrift für interkulturelle Germanistik
Heimböckel, Dieter UL; Mein, Georg UL; Schiewer, Lenore Gesine et al

in ZiG (2016), 7(1),

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See detailmiR-661 expression in SNAI1-induced epithelial to mesenchymal transition contributes to breast cancer cell invasion by targeting Nectin-1 and StarD10 messengers
Vetter, G.; Saumet, A.; Moes, Michèle UL et al

in Oncogene (2016), 35(5), 670

Epithelial to mesenchymal transition (EMT) is a key step toward metastasis. MCF7 breast cancer cells conditionally expressing the EMT master regulator SNAI1 were used to identify early expressed microRNAs ... [more ▼]

Epithelial to mesenchymal transition (EMT) is a key step toward metastasis. MCF7 breast cancer cells conditionally expressing the EMT master regulator SNAI1 were used to identify early expressed microRNAs (miRNAs) and their targets that may contribute to the EMT process. Potential targets of miRNAs were identified by matching lists of in silico predicted targets and of inversely expressed mRNAs. MiRNAs were ranked based on the number of predicted hits, highlighting miR-661, a miRNA with so far no reported role in EMT. MiR-661 was found required for efficient invasion of breast cancer cells by destabilizing two of its predicted mRNA targets, the cell-cell adhesion protein Nectin-1 and the lipid transferase StarD10, resulting, in turn, in the downregulation of epithelial markers. Reexpression of Nectin-1 or StarD10 lacking the 3'-untranslated region counteracted SNAI1-induced invasion. Importantly, analysis of public transcriptomic data from a cohort of 295 well-characterized breast tumor specimen revealed that expression of StarD10 is highly associated with markers of luminal subtypes whereas its loss negatively correlated with the EMT-related, basal-like subtype. Collectively, our non-a priori approach revealed a nonpredicted link between SNAI1-triggered EMT and the down-regulation of Nectin-1 and StarD10 through the up-regulation of miR-661, which may contribute to the invasion of breast cancer cells and poor disease outcome. [less ▲]

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See detailGroßschutzgebiete, Biodiversität und räumliche Planung
Heiland, Stefan; Jedicke, Eckhard; Job, Hubert et al

in Positionspapier aus der Akademie fuer Raumforschung und Landesplanung (2016), 107

Detailed reference viewed: 75 (3 UL)
See detailQualität frühkindlicher Bildung im europäischen Vergleich
Andersen, Katja Natalie UL

in KiTa aktuell HRS - Fachzeitschrift für Leitungen, Fachkräfte und Träger der Kindertagesbetreuung (2016), 24(5), 97

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See detailChronique Administration européenne Principes du droit administratif européen
Neframi, Eleftheria UL

in Revue Française d'Administration Publique (2015)

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See detailChronique Administration européenne Principes du droit administratif européen
Neframi, Eleftheria UL

in Revue Française d'Administration Publique (2015)

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See detailZeitschrift für interkulturelle Germanistik
Heimböckel, Dieter UL; Mein, Georg UL; Schiewer, Gesine Lenore et al

in ZiG (2015), 6(2),

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See detailAgainst the current: transboundary water management in small states on two continents
Koff, Harlan UL; Maganda, Carmen

in WATER INTERNATIONAL (2015), 40(2), 231-250

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See detailZeitschrift für interkulturelle Germanistik
Heimböckel, Dieter UL; Hess-Lüttich, Ernest W.B.; Mein, Georg UL et al

in ZiG (2015), 6(1),

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See detailResonant Enhancement of Magneto-Optical Activity Induced by Surface Plasmon Polariton Modes Coupling in 2D Magnetoplasmonic Crystals
Maccaferri, Nicolo UL; Inchausti, Xabier; Garcia-Martin, Antonio et al

in ACS PHOTONICS (2015), 2(12), 1769-1779

Magnetoplasmonic crystals are spatially periodic nanostructured magnetic surfaces combining the features of surface plasmon polariton excitation and magneto-optical tunability. Here we present a ... [more ▼]

Magnetoplasmonic crystals are spatially periodic nanostructured magnetic surfaces combining the features of surface plasmon polariton excitation and magneto-optical tunability. Here we present a comprehensive experimental and theoretical work demonstrating that in magnetoplasmonic crystals the coupling of free space radiation to surface plasmon polariton modes in conjunction with the inherent magneto-optical activity, enable cross-coupling of propagating surface plasmon polariton modes. We have explored the consequences of this unique magnetoplasmonic crystal optical feature by studying the light reflected from a two-dimensional periodic array of cylindrical holes in a ferromagnetic layer illuminated at oblique incidence and magnetized in the sample plane, namely, in the so-called longitudinal Kerr effect geometry. We observe that the magneto-optical spectral response arises from all the excitable surface plasmon polariton modes in the magnetoplasmonic crystal irrespective of the incoming light polarization. We show that this is a direct consequence of the magneto-optically mediated coupling of propagating surface plasmon polariton modes. We demonstrate that a large enhancement of the longitudinal Kerr effect is induced when special noncollinear surface plasmon polariton modes, which couple to both p- and s-polarized light, are resonantly excited. We show how the resonant enhancement of the Kerr effect can be set at desired radiation wavelengths and incidence angles by precise plasmonic band engineering achievable through the proper design of the magnetoplasmonic lattice structure. Our findings, besides clarifying the underlying physics that governs the peculiar magneto-optical properties of magnetoplasmonic crystals, open a path to the design of novel active metamaterials with tailored and enhanced magneto-optical activity. [less ▲]

See detailVernetzung von Theorie und Praxis: Herausforderungen an die Aus- und Weiterbildung im frühkindlichen Bereich
Andersen, Katja Natalie UL

in KiTa aktuell HRS - Fachzeitschrift für Leitungen, Fachkräfte und Träger der Kindertagesbetreuung (2015), 23(6), 123

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See detailHabilitationsschrift „Prinzipien der kollektiven Vermögensanlage“
Zetzsche, Dirk Andreas UL

in Habilitationsschrift „Prinzipien der kollektiven Vermögensanlage“, 1004 S., Jus Privatum 192 (2015)

Rezensiert von Köndgen, AG 2015, 839; Freitag, NZG 2015, 1306; Kreisl, ZFR 2016, 49-50; Binder, ZVglRW 2016, 293-298; Opitz, Der Gesellschafter 2016, 37; Heidinger, RDW (A) 2016, 155; Hanten, ZBB 2016 ... [more ▼]

Rezensiert von Köndgen, AG 2015, 839; Freitag, NZG 2015, 1306; Kreisl, ZFR 2016, 49-50; Binder, ZVglRW 2016, 293-298; Opitz, Der Gesellschafter 2016, 37; Heidinger, RDW (A) 2016, 155; Hanten, ZBB 2016, 218-227. [less ▲]

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See detailSprache und Identität: Aktivieren von Sprachressourcen bei Kindern
Andersen, Katja Natalie UL

in KiTa aktuell HRS - Fachzeitschrift für Leitungen, Fachkräfte und Träger der Kindertagesbetreuung (2015), 23(07/08), 147

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See detailOn being bicultural in a multicultural society
Murdock, Elke UL; Ferring, Dieter UL

in EARA - Newsletter - European Association for Research on Adolescence (2014)

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See detailPrenatal maternal stress and child developmental outcome: Implications for health care provision?
Pit-Ten Cate, Ineke UL

in Developmental Medicine & Child Neurology (2014), 56(3), 204-205

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See detailEffects of a non-absorbing substrate on the magneto-optical Kerr response of plasmonic ferromagnetic nanodisks
Maccaferri, Nicolo UL; Kataja, Mikko; Bonanni, Valentina et al

in PHYSICA STATUS SOLIDI A-APPLICATIONS AND MATERIALS SCIENCE (2014), 211(5), 1067-1075

Magnetoplasmonics is an emerging field of intense research on materials combining magnetic and plasmonic functionalities. The novel optical and magneto-optical (MO) properties displayed by these materials ... [more ▼]

Magnetoplasmonics is an emerging field of intense research on materials combining magnetic and plasmonic functionalities. The novel optical and magneto-optical (MO) properties displayed by these materials could allow the design of a new class of magnetically controllable optical nano-devices. In this work, we investigate the effects of a non-absorbing (insulating) substrate on the MO activity of pure ferromagnetic disk-shaped nanostructures supporting localized plasmon resonances. We show that the red-shift of the localized plasmon resonance, related to the modification of the localization of the electromagnetic field due to the substrate, is not the only effect that the substrate has on the MO response. We demonstrate that the reflectivity of the substrate itself plays a key role in determining the MO response of the system. We discuss why it is so and provide a description of the modeling tools suitable to take into account both effects. Understanding the role of the substrate will permit a more aware design of magnetoplasmonic nanostructured devices for future biotechnological and optoelectronic applications. [GRAPHICS] Ferromagnetic nickel nanodisk in vacuum (left) and on a non-absorbing substrate (right), illuminated by linearly polarized light. The polarization of the reflected field is changed in the first case due to a combination of intrinsic magneto-optical properties and the nanoconfinement of the material. In the second case, the polarization of the reflected light is affected also by the presence of the substrate. (C) 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim [less ▲]

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See detailState of the Art in der Verhaltensmedizin: Keynote-Beiträge der DGVM-Jahrestagung 2013 - Editorial
Vögele, Claus UL; Leplow, Bernd; Hillert, Andreas

in Verhaltenstherapie (2014)

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See detailZeitschrift für interkulturelle Germansitik
Heimböckel, Dieter UL; Hess-Lüttich, Ernest W.B; Mein, Georg UL et al

in ZiG (2014), 5(2),

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See detailZeitschrift für interkulturelle Germansitik
Heimböckel, Dieter UL; Hss-Lüttich, Ernest; Mein, Georg UL et al

in ZiG (2014), 5(1),

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See detailPädagogische Konzepte
Andersen, Katja Natalie UL

in KiTa aktuell HRS - Fachzeitschrift für Leitungen, Fachkräfte und Träger der Kindertagesbetreuung (2014), 22(9), 191

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See detailConviviality-Driven Access Control Policy
El Kateb, Donia UL; Zannone, Nicola; Moawad, Assaad UL et al

in Requirements Engineering (2014)

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See detailThe sequential isolation of metabolites, RNA, DNA, and proteins from a single, undivided mixed microbial community sample
Muller, Emilie UL; Buschart, Anna UL; Roume, Hugo UL et al

in Protocol Exchange (2014)

Integrated omics of microbial consortia, comprising systematized metagenomic, metatranscriptomic, metaproteomic and meta-metabolomic analyses, allows in-depth characterization of organismal and functional ... [more ▼]

Integrated omics of microbial consortia, comprising systematized metagenomic, metatranscriptomic, metaproteomic and meta-metabolomic analyses, allows in-depth characterization of organismal and functional diversity in situ. To allow meaningful meta-omic data integration, truly systematic measurements of the typically heterogeneous sample biomass is required. Therefore, there is a need for analyzing biomolecular fractions obtained from single, undivided samples. Here, we share a methodological workflow for the reproducible isolation of concomitant polar and non-polar metabolites, RNA, DNA and proteins from samples obtained from a biological wastewater treatment plant. The methodological framework is applicable to other biological samples [1,2], is compatible with different kits for biomacromolecular isolation [1,2] with minimal tailoring, and represents an important first step in standardization for the emerging field of Molecular Eco-Systems Biology. [less ▲]

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See detailChronique Administration européenne, Principes du droit administratif européen
Neframi, Eleftheria UL

in Revue Française d'Administration Publique (2014)

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See detail« Mesures d’instruction », Fasc. JCL procédure civile 634
Menetrey, Séverine UL

in JurisClasseur Procédure civile (2013)

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See detailPsychische Erkrankungen
Andersen, Katja Natalie UL

in KiTa aktuell HRS- Fachzeitschrift für Leitungen, Fachkräfte und Träger der Kindertagesbetreuung (2013), 21(11), 255

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See detailZeitschrift für interkulturelle Germanistik
Heimböckel, Dieter UL; Hess-Lüttich, Ernest W.B.; Mein, Georg UL et al

in ZiG (2013), 4(1),

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See detailChronique Administration européenne, Principes du droit administratif européen
Neframi, Eleftheria UL

in Revue Française d'Administration Publique (2013)

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See detailReport on the International Workshop "Value of Children and Intergenerational Relations ", March 29th to 30th, 2012, at the University of Konstanz, organized by Gisela Trommsdorff and Bernhard Nauck
Ziehm, Jeanette; Albert, Isabelle UL

in Zeitschrift für Soziologie der Erziehung und Sozialisation = Journal for Sociology of Education and Socialization (2013), 33

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See detailZeitschrift für interkulturelle Germanistik
Heimböckel, Dieter UL; Hess-Lüttich, Ernest W.B.; Mein, Georg UL et al

in ZiG (2013), 4(2),

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See detailStepwise, non-adherent differentiation of human pluripotent stem cells to generate basal forebrain cholinergic neurons via hedgehog signaling
Crompton, Lucy A.; Byrne, Meg L.; Taylor, Hannah et al

in STEM CELL RESEARCH (2013), 11(3), 1206-1221

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See detailEating healthily: a task for health education?
Vögele, Claus UL

in Agro Food Industry Hi Tech (2013), 23(6), 3-3

Editorial

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See detailSpecial issue on evolutionary computing and complex systems
Bouvry, Pascal UL; Schuetze, Oliver; Coello Coello, Carlos A. et al

in SOFT COMPUTING (2013), 17(6), 909-912

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See detailChronique Administration européenne, Principes du droit administratif européen
Neframi, Eleftheria UL

in Revue Française d'Administration Publique (2012)

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See detailReply to Comment on Fast and Accurate Modeling of Molecular Atomization Energies with Machine Learning
Rupp, M.; Tkatchenko, Alexandre UL; Müller, K.-R. et al

in Physical Review Letters (2012), 109(5),

[No abstract available]

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See detailThe normalized CES production function: theory and empirics
Klump, Rainer UL; McAdam, Peter; Willman, Alpo

in JOURNAL OF ECONOMIC SURVEYS (2012), 26(5), 769-799

The elasticity of substitution between capital and labor and, in turn, the direction of technical change are critical parameters in many fields of economics. Until recently, though, the application of ... [more ▼]

The elasticity of substitution between capital and labor and, in turn, the direction of technical change are critical parameters in many fields of economics. Until recently, though, the application of production functions with specifically non-unitary substitution elasticities (i.e., non-CobbDouglas) was hampered by empirical and theoretical uncertainties. As recently revealed, normalization of production-technology systems holds out the promise of resolving many of those uncertainties. We survey and assess the intrinsic links between production (as conceptualized in a production function), factor substitution (as made most explicit in Constant Elasticity of Substitution functions) and normalization (defined by the fixing of baseline values for relevant variables). First, we recall how the normalized Constant Elasticity of Substitution function came into existence and what normalization implies for its formal properties. Then we deal with the key role of normalization in recent advances in the theory of business cycles and of economic growth. Next, we discuss the benefits normalization brings for empirical estimation and empirical growth research. Finally, we identify promising areas of future research. [less ▲]

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See detailSpecial issue on satellite communication systems and networking
Panagopoulos, A. D.; Scalise, S.; Ottersten, Björn UL et al

in Eurasip Journal on Wireless Communications and Networking (2012), 2012

[No abstract available]

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See detailZeitschrift für interkulturelle Germanistik
Heimböckel, Dieter UL; Hess-Lüttich, Ernest W.B.

in ZiG (2012), 3(2),

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See detailStudies in Philosophy and Education Volume 31
Biesta, Gert UL

in Studies in Philosophy & Education (2012)

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See detailThe duration and durability of cabinet ministers
Fischer, Joern; Dowding, Keith; Dumont, Patrick UL

in INTERNATIONAL POLITICAL SCIENCE REVIEW (2012), 33(5), 505-519

This article surveys the growing research programme on the duration of cabinet ministers. It examines some of the conceptual and methodological issues confronting research, including the nature and ... [more ▼]

This article surveys the growing research programme on the duration of cabinet ministers. It examines some of the conceptual and methodological issues confronting research, including the nature and measurement of durability, ministerial terms and techniques. It considers some of the theories and hypotheses that have been generated by researchers. Using evidence from studies from around the world, it argues that institutional factors, including regime type, constitutional and parliamentary rules, and party systems, affect ministerial durability. Personal ministerial characteristics, such as gender, education and age, also affect durability. It examines future avenues of research in this field. [less ▲]

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See detailZeitschrift für interkulturelle Germanistik
Heimböckel, Dieter UL; Hess-Lüttich, Ernest W.B.; Mein, Georg UL et al

in ZiG (2012), 3(2),

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See detailHydrogen-Bonded Networks Along and Bifurcation of the E-Pathway in Quinol:Fumarate Reductase
Herzog, Elena; Gu, Wei UL; Juhnke, Hanno D. et al

in Biophysical Journal (2012), 103(6), 1305-1314

The E-pathway of transmembrane proton transfer has been demonstrated previously to be essential for catalysis by the diheme-containing quinol:fumarate reductase (QFR) of Wolinella succinogenes. Two ... [more ▼]

The E-pathway of transmembrane proton transfer has been demonstrated previously to be essential for catalysis by the diheme-containing quinol:fumarate reductase (QFR) of Wolinella succinogenes. Two constituents of this pathway, Glu-C180 and heme bp ring C (b(D)-C-) propionate, have been validated experimentally. Here, we identify further constituents of the E-pathway by analysis of molecular dynamics simulations. The redox state of heme groups has a crucial effect on the connectivity patterns of mobile internal water molecules that can transiently support proton transfer from the b(D)-C-propionate to Glu-C180. The short H-bonding paths formed in the reduced states can lead to high proton conduction rates and thus provide a plausible explanation for the required opening of the E-pathway in reduced QFR. We found evidence that the b(D)-C-propionate group is the previously postulated branching point connecting proton transfer to the E-pathway from the quinol-oxidation site via interactions with the heme bp ligand His-C44. An essential functional role of His-C44 is supported experimentally by site-directed mutagenesis resulting in its replacement with Glu. Although the H44E variant enzyme retains both heme groups, it is unable to catalyze quinol oxidation. All results obtained are relevant to the QFR enzymes from the human pathogens Campylobacter jejuni and Helicobacter pylori. [less ▲]

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See detailChronique Administration européenne, Principes du droit administratif européen
Neframi, Eleftheria UL

in Revue Française d'Administration Publique (2012)

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See detailCarbon Nanotube Wins the Competitive Binding over Proline-Rich Motif Ligand on SH3 Domain
Zuo, Guanghong; Gu, Wei UL; Fang, Haiping et al

in JOURNAL OF PHYSICAL CHEMISTRY C (2011), 115(25), 12322-12328

The binding competition between a proline-rich motif (PRM) ligand and a hydrophobic nanoparticle, the single-wall carbon nanotube (SWCNT), at the binding pocket of SH3 domain, has been investigated by ... [more ▼]

The binding competition between a proline-rich motif (PRM) ligand and a hydrophobic nanoparticle, the single-wall carbon nanotube (SWCNT), at the binding pocket of SH3 domain, has been investigated by molecular dynamics simulations. It is found that the SWCNT has a very high probability of occupying the binding pocket of the SH3 domain, which prevents the PRM ligand from binding to the pocket. The binding free energy landscapes show that the SWCNT has similar to 0.6 kcal/mol stronger binding affinity than the ligand in the three-way binding competition (SWCNT + ligand + protein). The potent binding affinity between the SWCNT and the SH3 domain is shown to be mainly from the pi-pi stacking interactions between the CNT and aromatic residues in the binding pocket. Our findings show that the existence of hydrophobic particles can greatly reduce the possibility of the regular binding of the ligand with the target protein, suggesting potential toxicity to proteins by hydrophobic nanoscale particles. [less ▲]

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See detailA systems biology approach towards understanding nuclear receptor interactions: Implications at the endocrine-xenobiotic signalling interface
Kolodkin, Alexey UL; Phillips, Anna; Hood, Steve et al

in Toxicology (2011), 290(2-3), 131-131

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See detailZeitschrift für interkulturelle Germanistik
Heimböckel, Dieter UL; Hess-Lüttich, Ernest W.B.; Mein, Georg UL et al

in ZiG (2011), 2(2),

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See detailDesign of a Gated Molecular Proton Channel
Gu, Wei UL; Zhou, Bo; Geyer, Tihamer et al

in Angewandte Chemie International Edition (2011), 50(3), 768-771

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See detailAdhesive water networks facilitate binding of protein interfaces
Ahmad, Mazen; Gu, Wei UL; Geyer, Tihamer et al

in Nature Communications (2011), 2

Water structure has an essential role in biological assembly. Hydrophobic dewetting has been documented as a general mechanism for the assembly of hydrophobic surfaces; however, the association mechanism ... [more ▼]

Water structure has an essential role in biological assembly. Hydrophobic dewetting has been documented as a general mechanism for the assembly of hydrophobic surfaces; however, the association mechanism of hydrophilic interfaces remains mysterious and cannot be explained by simple continuum water models that ignore the solvent structure. Here we study the association of two hydrophilic proteins using unbiased extensive molecular dynamics simulations that reproducibly recovered the native bound complex. The water in the interfacial gap forms an adhesive hydrogen-bond network between the interfaces stabilizing early intermediates before native contacts are formed. Furthermore, the interfacial gap solvent showed a reduced dielectric shielding up to distances of few nanometres during the diffusive phase. The interfacial gap solvent generates an anisotropic dielectric shielding with a strongly preferred directionality for the electrostatic interactions along the association direction. [less ▲]

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See detailZeitschrift für interkulturelle Germanistik
Heimböckel, Dieter UL; Hess-Lüttich, Ernest W.B.; Mein, Georg UL et al

in ZiG (2011), 2(1),

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See detailChronique de la jurisprudence de la Cour de justice de l'Union européenne
Neframi, Eleftheria UL; Monjal, Pierre Yves; Vallindas, Georgios

in Revue hellénique de droit international (2011)

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See detailChronique Administration européenne, Principes du droit administratif européen
Neframi, Eleftheria UL

in Revue Française d'Administration Publique (2011)

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See detailStudies in Philosophy and Education Volume 30
Biesta, Gert UL

in Studies in Philosophy & Education (2011)

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See detailRon Scollon (1939-2009): An academic in the wild
Norris, Sigrid; Castillo-Ayometzi, Cecilia; de Saint-Georges, Ingrid UL et al

in Discourse & Society (2011), 22(2), 209-216

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See detailChronique Administration européenne, Principes du droit administratif européen
Neframi, Eleftheria UL

in Revue Française d'Administration Publique (2011)

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See detailWho gets what in coalition governments? Predictors of portfolio allocation in parliamentary democracies
Bäck, Hanna; Debus, Marc; Dumont, Patrick UL

in EUROPEAN JOURNAL OF POLITICAL RESEARCH (2011), 50(4), 441-478

Ministerial portfolios are the most obvious payoffs for parties entering a governing coalition in parliamentary democracies. This renders the bargaining over portfolios an important phase of the ... [more ▼]

Ministerial portfolios are the most obvious payoffs for parties entering a governing coalition in parliamentary democracies. This renders the bargaining over portfolios an important phase of the government formation process. The question of 'who gets what, and why?' in terms of ministerial remits has not yet received much attention by coalition or party scholars. This article focuses on this qualitative aspect of portfolio allocation and uses a new comparative dataset to evaluate a number of hypotheses that can be drawn from the literature. The main hypothesis is that parties which, in their election manifestos, emphasise themes corresponding to the policy remit of specific cabinet portfolios are more likely to obtain control over these portfolios. The results show that policy saliency is indeed an important predictor of portfolio allocation in postwar Western European parliamentary democracies. [less ▲]

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See detailChronique de la jurisprudence de la Cour de justice de l'Union européenne
Neframi, Eleftheria UL

in Revue Hellénique de Droit International (2010)

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See detailDownhill Binding Energy Surface of the Barnase-Barstar Complex
Wang, Ling; Siu, Shirley W. I.; Gu, Wei UL et al

in Biopolymers (2010), 93(11), 977-985

We have employed biased molecular dynamics simulations in explicit solvent to characterize the one-dimensional potential of mean force for the dissociation process of the barnase-barstar protein-protein ... [more ▼]

We have employed biased molecular dynamics simulations in explicit solvent to characterize the one-dimensional potential of mean force for the dissociation process of the barnase-barstar protein-protein complex. Unbinding of barstar from wild-type barnase was compared with dissociation from four charge-deletion mutants of barnase. Interestingly, we find in all cases that unbinding of barnase and barstar is an uphill process on a smooth, tilted energy landscape. The total free energy difference between the dissociated and bound state was similar for wild-type barnase-barstar and for the R87A mutant of barnase. The values for the three other mutant barnase mutants K27A, R59A, and R83Q were only about half as much. Besides, we have analyzed the conformational dynamics of important residues at the barnase-barstar interface. In the bound state, their conformational fluctuations are reduced relatively to the free state because of the formation of intermolecular contacts. Interestingly, we find that some residues also show decreased mobility at intermediate stages of the unbinding process suggesting that these residues may be involved in the first contacts being formed on binding. (C) 2010 Wiley Periodicals, Inc. Biopolymers 93: 977-985, 2010. [less ▲]

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See detailAtomistic Simulation of Water Percolation and Proton Hopping in Nation Fuel Cell Membrane
Devanathan, Ram; Venkatnathan, Arun; Rousseau, Roger et al

in Journal of Physical Chemistry B (2010), 114(43), 13681-13690

We have performed a detailed analysis of water clustering and percolation in hydrated Nafion configurations generated by classical molecular dynamics simulations. Our results show that at low hydration ... [more ▼]

We have performed a detailed analysis of water clustering and percolation in hydrated Nafion configurations generated by classical molecular dynamics simulations. Our results show that at low hydration levels H(2)O molecules are isolated and a continuous hydrogen-bonded network forms as the hydration level is increased. Our quantitative analysis has established a hydration level (lambda) between 5 and 6 H(2)O/SO(3)(-) as the percolation threshold of Nation. We have also examined the effect of such a network on proton transport by studying the structural diffusion of protons using the quantum hopping molecular dynamics method. The mean residence time of the proton on a water molecule decreases by 2 orders of magnitude when the lambda value is increased from 5 to 15. The proton diffusion coefficient in Nation at a lambda value of 15 is about 1.1 x 10(-5) cm(2)/s in agreement with experiment. The results provide quantitative atomic-level evidence of water network percolation in Nafion and its effect on proton conductivity. [less ▲]

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See detailPedagogies in context: Perspectives on contemporary Spain
Budach, Gabriele UL

in Linguistics and Education (2010), 21(3), 244-255

[No abstract available]

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See detailChronique Administration européenne, Principes du droit administratif européen
Neframi, Eleftheria UL

in Revue Française d'Administration Publique (2010)

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See detailNuclear receptors as controlling factors in chemical metabolism: Determination of regulatory signal network crucial for co-ordinating cellular response to chemicals
Kolodkin, Alexey UL; Phillips, Anna; Hood, Steve R. et al

in Drug Metabolism Reviews (2010), 42(1), 279-280

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See detailStudies in Philosophy and Education Volume 29
Biesta, Gert UL

in Studies in Philosophy & Education (2010)

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See detailZeitschrift für interkulturelle Germanistik
Heimböckel, Dieter UL; Hess-Lüttich, Ernest W.B.; Mein, Georg UL et al

in ZiG (2010), 1(2),

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See detailZeitschrift für interkulturelle Germanistik
Hess-Lüttich, Ernest; Mein, Georg UL; Sieburg, Heinz UL et al

in ZiG (2010), 1(1),

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See detailChronique de jurisprudence du Tribunal de l'Union européenne
Neframi, Eleftheria UL; Vallindas, George

in Annuaire de Droit Européen (2009)

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See detailStudies in Philosophy and Education Volume 28
Biesta, Gert UL

in Studies in Philosophy & Education (2009), 28

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See detailDoes European Integration Lead to a 'Presidentialization' of Executive Politics? Ministerial Selection in Swedish Postwar Cabinets
Bäck, Hanna; Dumont, Patrick UL; Meier, Henk Erik et al

in EUROPEAN UNION POLITICS (2009), 10(2), 226-252

In this article, we address recent claims that executive legislative relations in parliamentary democracies are undergoing important changes owing to either a 'presidentialization' or a 'Europeanization ... [more ▼]

In this article, we address recent claims that executive legislative relations in parliamentary democracies are undergoing important changes owing to either a 'presidentialization' or a 'Europeanization' of domestic political systems. Therefore, we test empirically whether parliamentary democracies are indeed experiencing changes in executive-legislative relations and whether these developments can, in part, be explained by an increase in European integration. Using data on ministerial selection in Swedish cabinets during the years 1952-2006, we find that there appears to be a slight tendency towards 'presidentialization', which is indicated by a decrease in ministers with a parliamentary background being appointed, and that there exists some support for the notion that Sweden's political and economic integration into the European Union is part of the explanation for this change. [less ▲]

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See detailTightly Connected Water Wires Facilitate Fast Proton Uptake at The Proton Entrance of Proton Pumping Proteins
Gu, Wei UL; Helms, Volkhard

in Journal of the American Chemical Society (2009), 131(6), 2080-

Tightly connected water wires (TCW) exist in systems with nonconfined water like the solvated membrane proton pump system. The TCWs that connect to the negatively charged proton entrance facilitate the ... [more ▼]

Tightly connected water wires (TCW) exist in systems with nonconfined water like the solvated membrane proton pump system. The TCWs that connect to the negatively charged proton entrance facilitate the fast proton uptake of the proton pump. They function as a direct proton bridge or/and stabilizer of protons within the Coulomb cage of the proton entrance. Negatively charged residue(s) at the proton entrance induce a large population of long TCWs. Additional negatively charged residues increase the population of such long TCWs and, thus, raise the possibility to capture proton from the solution. [less ▲]

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