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See detail4D Biology for health and disease
Abrahams, J. P.; Apweiler, R.; Balling, Rudi UL et al

in New Biotechnology (2011), 28(4), 291-293

The "4D Biology Workshop for Health and Disease", held on 16-17th of March 2010 in Brussels, aimed at finding the best organising principles for large-scale proteomics, interactomics and structural ... [more ▼]

The "4D Biology Workshop for Health and Disease", held on 16-17th of March 2010 in Brussels, aimed at finding the best organising principles for large-scale proteomics, interactomics and structural genomics/biology initiatives, and setting the vision for future high-throughput research and large-scale data gathering in biological and medical science. Major conclusions of the workshop include the following. (i) Development of new technologies and approaches to data analysis is crucial. Biophysical methods should be developed that span a broad range of time/spatial resolution and characterise structures and kinetics of interactions. Mathematics, physics, computational and engineering tools need to be used more in biology and new tools need to be developed. (ii) Database efforts need to focus on improved definitions of ontologies and standards so that system-scale data and associated metadata can be understood and shared efficiently. (iii) Research infrastructures should play a key role in fostering multidisciplinary research, maximising knowledge exchange between disciplines and facilitating access to diverse technologies. (iv) Understanding disease on a molecular level is crucial. System approaches may represent a new paradigm in the search for biomarkers and new targets in human disease. (v) Appropriate education and training should be provided to help efficient exchange of knowledge between theoreticians, experimental biologists and clinicians. These conclusions provide a strong basis for creating major possibilities in advancing research and clinical applications towards personalised medicine. [less ▲]

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See detail4th Conference on Poisson Geometry and related fields
Poncin, Norbert UL

Report (2004)

Speakers' abstracts and list of participants of the International Conference on 'Poisson Geometry and related fields' organized in June 2004 at the University of Luxembourg by Norbert Poncin

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See detail5 Figures de l’Histoire des idées européennes ou la recherche de la Communauté politique
Poirier, Philippe UL

in Arjakovsky, Antoine (Ed.) Histoire de la conscience européenne (2016)

Il ne s’agit pas de produire un récit exhaustif ou apologétique ou exclusif de la conscience européenne. Il s’agit de rendre visible la réalité mouvante d’une conscience européenne qui s’affirme de plus ... [more ▼]

Il ne s’agit pas de produire un récit exhaustif ou apologétique ou exclusif de la conscience européenne. Il s’agit de rendre visible la réalité mouvante d’une conscience européenne qui s’affirme de plus en plus en Europe. Pour n’avoir aucun lieu où se penser et où se refléter, celle-ci est bien souvent abandonnée à elle-même au point de douter de sa réalité propre. Mais les enjeux politiques, économiques et culturels de l’Europe politique sont tels que l’Union européenne ne pourra plus se permettre trop longtemps de se passer de récit commun. [less ▲]

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See detail5-Carboxy-8-hydroxyquinoline is a Broad Spectrum 2-Oxoglutarate Oxygenase Inhibitor which Causes Iron Translocation.
Hopkinson, Richard J.; Tumber, Anthony; Yapp, Clarence et al

in Chemical Science (2013), 4(8), 3110-3117

2-Oxoglutarate and iron dependent oxygenases are therapeutic targets for human diseases. Using a representative 2OG oxygenase panel, we compare the inhibitory activities of 5-carboxy-8-hydroxyquinoline ... [more ▼]

2-Oxoglutarate and iron dependent oxygenases are therapeutic targets for human diseases. Using a representative 2OG oxygenase panel, we compare the inhibitory activities of 5-carboxy-8-hydroxyquinoline (IOX1) and 4-carboxy-8-hydroxyquinoline (4C8HQ) with that of two other commonly used 2OG oxygenase inhibitors, N-oxalylglycine (NOG) and 2,4-pyridinedicarboxylic acid (2,4-PDCA). The results reveal that IOX1 has a broad spectrum of activity, as demonstrated by the inhibition of transcription factor hydroxylases, representatives of all 2OG dependent histone demethylase subfamilies, nucleic acid demethylases and gamma-butyrobetaine hydroxylase. Cellular assays show that, unlike NOG and 2,4-PDCA, IOX1 is active against both cytosolic and nuclear 2OG oxygenases without ester derivatisation. Unexpectedly, crystallographic studies on these oxygenases demonstrate that IOX1, but not 4C8HQ, can cause translocation of the active site metal, revealing a rare example of protein ligand-induced metal movement. [less ▲]

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See detail5. Changes in the stratification process in Israel, 1995--2008
Blank, Carmel; Bar-Haim, Eyal UL; Shavit, Yossi

in Education, Occupation and Social Origin: A Comparative Analysis of the Transmission of Socio-Economic Inequalities (2016)

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See detail50 Jahre Stadtgeschichtsschreibung zur Stadt Luxemburg
Pauly, Michel UL

in Hemecht : Zeitschrift für Luxemburger Geschichte = Revue d'Histoire Luxembourgeoise (2011), 63(2), 173-200

Bibliografische Übersicht über historische Forschung zur Stadt Luxemburg 1963-2012

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See detail50 Ways to Break RFID Privacy
van Deursen, Ton UL

in Privacy and Identity Management for Life (2011), 352

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See detail55. Aktualisierungslieferung - Entstehungsgeschichte 14. und 15 RÄStV; §§ 8a, 13, 16 RStV
Cole, Mark UL; Hartstein; Ring et al

Book published by Jehle-Rehm (2013)

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See detail550 GHz bandwidth photodetector on low-temperature grown molecular-beam epitaxial GaAs
Kordoš, P.; Förster, A.; Marso, Michel UL et al

in Electronics Letters (1998), 34(1998), 119-120

The authors demonstrate that a 550GHz bandwidth photodetector can be fabricated on low-temperature grown MBE GaAs. The pulse response shows 0.4 and 0.6ps rise and fall times, respectively. The bandwidth ... [more ▼]

The authors demonstrate that a 550GHz bandwidth photodetector can be fabricated on low-temperature grown MBE GaAs. The pulse response shows 0.4 and 0.6ps rise and fall times, respectively. The bandwidth is in agreement with a value calculated using a carrier lifetime of 0.2ps, measured by femtosecond time-resolved reflectivity, and a capacitance of 0.014fF/um2, determined from microwave measurements. The device bandwidth is RC limited. [less ▲]

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See detail56. Aktualisierungslieferung - §§ 14, 43, 52b, 62, 64 RStV
Cole, Mark UL; Hartstein; Ring et al

Book published by Jehle-Rehm (2013)

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See detail5D Super Yang-Mills on Y p,q Sasaki-Einstein manifolds
Qiu, Jian UL; Zabzine, Maxim

E-print/Working paper (2013)

On any simply connected Sasaki-Einstein five dimensional manifold one can construct a super Yang-Mills theory which preserves at least two supersymmetries. We study the special case of toric Sasaki ... [more ▼]

On any simply connected Sasaki-Einstein five dimensional manifold one can construct a super Yang-Mills theory which preserves at least two supersymmetries. We study the special case of toric Sasaki-Einstein manifolds known as Y p,q manifolds. We use the localisation technique to compute the full perturbative part of the partition function. The full equivariant result is expressed in terms of certain special function which appears to be a curious generalisation of the triple sine function. As an application of our general result we study the large N behaviour for the case of single hypermultiplet in adjoint representation and we derive the N 3-behaviour in this case. [less ▲]

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See detail5D super Yang-Mills on Yp,q Sasaki-Einstein manifolds
Qiu, Jian UL; Zabzine, Maxim

in Communications in Mathematical Physics (2015), 333(2),

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See detail5th international workshop on principles of engineering service-oriented systems (PESOS 2013)
Bianculli, Domenico UL; Lago, Patricia; Lewis, Grace et al

in Proceedings of the 2013 International Conference on Software Engineering (ICSE '13), San Francisco, CA USA (2013)

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See detail6. Images and Identities
Dell, Paul UL; Amann, Wilhelm UL; Bourg, Viviane UL et al

in IPSE (Ed.) Doing Identity in Luxembourg / Subjective Appropriations - Institutional Attributions- Soco-Cultural Milieus (2011)

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See detail60 bougies pour un projet impérial original
Scuto, Denis UL

Article for general public (2017)

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See detail6TiSCH Centralized Scheduling: when SDN Meet IoT
Thubert, Pascal; Palattella, Maria Rita UL; Engel, Thomas UL

in Proc. of IEEE Conf. on Standards for Communications & Networking (CSCN’15) (2015)

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See detail6TiSCH Wireless Industrial Networks: Determinism meet IPv6
Palattella, Maria Rita UL; Thubert, Pascal; Vilajosana, Xavier et al

in Internet of Things: Challenges and Opportunities. Lecture series of Smart Sensors, Measurements, and Instrumentation. vol 9 (2014)

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See detail70S-scanning initiation is a novel and frequent initiation mode of ribosomal translation in bacteria.
Yamamoto, Hiroshi; Wittek, Daniela; Gupta, Romi et al

in Proceedings of the National Academy of Sciences of the United States of America (2016), 113(9), 1180-9

According to the standard model of bacterial translation initiation, the small ribosomal 30S subunit binds to the initiation site of an mRNA with the help of three initiation factors (IF1-IF3). Here, we ... [more ▼]

According to the standard model of bacterial translation initiation, the small ribosomal 30S subunit binds to the initiation site of an mRNA with the help of three initiation factors (IF1-IF3). Here, we describe a novel type of initiation termed "70S-scanning initiation," where the 70S ribosome does not necessarily dissociate after translation of a cistron, but rather scans to the initiation site of the downstream cistron. We detailed the mechanism of 70S-scanning initiation by designing unique monocistronic and polycistronic mRNAs harboring translation reporters, and by reconstituting systems to characterize each distinct mode of initiation. Results show that 70S scanning is triggered by fMet-tRNA and does not require energy; the Shine-Dalgarno sequence is an essential recognition element of the initiation site. IF1 and IF3 requirements for the various initiation modes were assessed by the formation of productive initiation complexes leading to synthesis of active proteins. IF3 is essential and IF1 is highly stimulating for the 70S-scanning mode. The task of IF1 appears to be the prevention of untimely interference by ternary aminoacyl (aa)-tRNA*elongation factor thermo unstable (EF-Tu)*GTP complexes. Evidence indicates that at least 50% of bacterial initiation events use the 70S-scanning mode, underscoring the relative importance of this translation initiation mechanism. [less ▲]

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