References of "1990"
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See detailLes instruments de paiement et de crédit (1980-1989)
Dal, Georges-Albert; Corbisier, Isabelle UL

in Journal des Tribunaux (1990), (5554), 429-442

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See detailPouvoir et transparence dans la relation thérapeutique
Corbisier, Isabelle UL

in Revue Générale des Assurances et des Responsabilités [=RGAR] (1990), (11682), 19

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See detailLest we forget - Vergessen verhindern
Scuto, Denis UL

Article for general public (1990)

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See detailWat maache mer ? Wou gi mer ? : verwirrende Gedanken zur "Zeit der grossen Verwirrung"
Scuto, Denis UL

Article for general public (1990)

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See detailWas wird nun ? Die Evakuierung der Südbevölkerung und die Anfänge der deutschen Okkupation
Scuto, Denis UL

Article for general public (1990)

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See detailLuxemburg in den 30er Jahren - Leben mit der Bedrohung
Scuto, Denis UL

Article for general public (1990)

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See detailEine regressionsanalytische Alternative zum Wardschen Modell
Krolak-Schwerdt, Sabine UL; Orlik, Peter

Scientific Conference (1990, March)

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See detailKrichever-Novikov algebras for more than two points: explicit generators
Schlichenmaier, Martin UL

in Letters in Mathematical Physics (1990), 19(4), 327-336

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See detailDevelopment(s) in mouse genetics.
Balling, Rudi UL; Kessel, M.

in Biochemistry & Cell Biology (1990), 68(2), 404-7

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See detailCardiac baroreflex function during postural change using non-invasive spontaneous sequence analysis in young men.
Steptoe, Andrew; Vögele, Claus UL

in Cardiovascular Research (1990), 24

STUDY OBJECTIVE: The aim was to assess the value of baroreflex sensitivity estimates calculated from analyses of spontaneous systolic blood pressure and pulse interval sequences derived from continuous ... [more ▼]

STUDY OBJECTIVE: The aim was to assess the value of baroreflex sensitivity estimates calculated from analyses of spontaneous systolic blood pressure and pulse interval sequences derived from continuous non-invasive finger blood pressure recordings during sitting and active standing. DESIGN: Continuous recordings of digital systolic blood pressure and pulse interval were obtained non-invasively using a Finapres FD5 during 5 min trials of sitting and standing. SUBJECTS: Subjects were healthy males aged 19-28, divided into those with "high" normal (n = 18) and "low" normal (n = 17) blood pressure. MEASUREMENTS AND MAIN RESULTS: Recordings were scanned for spontaneous sequences of three or more cardiac cycles over which systolic blood pressure increased progressively in conjunction with prolonged pulse interval, or decreased while pulse interval became shorter. Regressions between blood pressure and pulse interval (r greater than 0.80) provided estimates of cardiac baroreceptor reflex control. Computations were carried out with concurrent blood pressure and pulse interval measurements, and with a delay or lag of one and two cycles between the two variables. Pulse interval was reduced from an average 870.3 ms sitting to 571.3 ms on standing. Mean baroreflex sensitivity while sitting averaged 17.5 ms.mm Hg-1 at a delay of one cycle, failing to 7.65 ms.mm Hg-1 with standing. The decrease in sensitivity was correlated with the change in pulse interval between trials. The number of sequences was also significantly reduced with standing as opposed to sitting. Three cycle sequences were most frequent, with a lesser number of sequences involving 4, 5, and 6 or more cycles. No significant differences between "high" and "low" normal blood pressure groups were observed. CONCLUSIONS: The analysis of spontaneous sequences from non-invasive recordings may provide useful information concerning cardiac baroreflex control in different postural and behavioural states. A lag of one cycle between systolic blood pressure and pulse interval may provide the most representative estimates of baroreflex sensitivity. [less ▲]

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See detailTumorigenesis and eye abnormalities in transgenic mice expressing MSV-SV40 large T-antigen.
Theuring, F.; Gotz, W.; Balling, Rudi UL et al

in Oncogene (1990), 5(2), 225-32

Transgenic mice which expressed SV40 large T-antigen under the control of the MSV enhancer and the SV40 promoter were generated. In animals containing an intact MSV enhancer, total lens cataracts and ... [more ▼]

Transgenic mice which expressed SV40 large T-antigen under the control of the MSV enhancer and the SV40 promoter were generated. In animals containing an intact MSV enhancer, total lens cataracts and neuroectodermal brain tumors, originating in the pineal organ were observed. In contrast, 5' deletion of the MSV enhancer to a residual 53 bp resulted in a different spectrum of pathologies. Whilst lens cataracts still occurred, no brain tumors could be detected. Instead, fibrosarcomas and adenocarcinomas of the kidneys were induced. In addition, tumors of the endocrine pancreas were observed with both transgene constructs. We conclude that the MSV enhancer element is sufficient to direct the expression of the viral reporter gene to the lens and the pineal organ in transgenic mice. Deletion of the MSV enhancer correlates with the loss of DNA elements responsible for the pineal cell specific expression of SV40 large T-antigen. [less ▲]

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See detailPerception et mesure du vieillissement durant la transition démographique. Ménage, profession, retraite : la place du vieillard dans la société, XVIIIe-XXe siècles
Leboutte, René UL

in Loriaux, Michel (Ed.) Chaire Quetelet 1986. Populations âgées et révolution grise. Les hommes et les sociétés face à leurs vieillissement. (1990)

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See detailOverexpression of a Streptomyces viridochromogenes gene (glnII) encoding a glutamine synthetase similar to those of eucaryotes confers resistance against the antibiotic phosphinothricyl-alanyl-alanine
Behrmann, Iris UL; Hillemann, D.; Pühler, A. et al

in Journal of Bacteriology (1990), 172(9), 5326-34

Phosphinothricyl-alanyl-alanine (PTT), also known as bialaphos, contains phosphinothricin, a potent inhibitor of glutamine synthetase (GS). A 2.75-kilobase NcoI fragment of the Streptomyces ... [more ▼]

Phosphinothricyl-alanyl-alanine (PTT), also known as bialaphos, contains phosphinothricin, a potent inhibitor of glutamine synthetase (GS). A 2.75-kilobase NcoI fragment of the Streptomyces viridochromogenes PTT-resistant mutant ES2 cloned on a multicopy vector mediated PTT resistance to S. lividans and to S. viridochromogenes. Nucleotide sequence analysis of the 2.75-kb NcoI fragment revealed the presence of three open reading frames. Open reading frame 3 was termed glnII since significant similarity was found between its deduced amino acid sequence and those from GS of eucaryotes and GSII of members of the family Rhizobiaceae. Subcloning experiments showed that PTT resistance is mediated by overexpression of glnII encoding a 37.3-kilodalton protein of 343 amino acids. A three- to fourfold increase in gamma-glutamyltransferase activity could be observed in S. lividans transformants carrying the glnII gene on a multicopy plasmid. For S. viridochromogenes it was shown that PTT resistance conferred by the 2.75-kb NcoI fragment was dependent on its multicopy state. GS activity encoded by glnII was found to be heat labile. Southern hybridization with seven different Streptomyces strains suggested that they all carry two types of GS genes, glnA and glnII. [less ▲]

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See detailTechnik im Saarbergbau - Historische Entwicklung und regionale Wirkung
Helfer, Malte UL

Book published by Akademie-Verlag (1990)

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See detailOxatomide and calcium: mechanisms involved in the secretion of mast cell mediators
Bueb, Jean-Luc UL; Landry, Y.

in Annales de Dermatologie et de Vénéréologie (1990), 117 Suppl 1

Human cutaneous mast cells and their experimental model rat peritoneal mast cells, can be stimulated by an IgE-dependent process or by peptides through the direct activation of G proteins. Both activation ... [more ▼]

Human cutaneous mast cells and their experimental model rat peritoneal mast cells, can be stimulated by an IgE-dependent process or by peptides through the direct activation of G proteins. Both activation pathways lead to the increase of cytosolic Ca2+ level. This increase in dependent of the mobilisation of intracellular calcium stores of the endoplasmic reticulum involving the stimulation of IP3-sensitive calcium channels. Mast cells are characterized by the absence of calcium channels in the plasma membrane. Oxatomide has been synthetized as an analog of cinnarizine. However oxatomide is inactive on current calcium channels. In mast cells, oxatomide inhibits the increase of cytosolic calcium elicited during mast cell activation. Consequently mast cell exocytosis is inhibited altogether with the release of newly synthetized mediators. The authors propose several putative targets for oxatomide in mast cells. The therapeutic effect of oxatomide is also related to its property to antagonize the effects of anaphylactic mediators on their selective receptors. [less ▲]

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See detailThe role of homeobox genes in mammalian development
Kessel, M; Balling, Rudi UL; Gruss, P

in Developmental Endocrinology (1990)

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